Protein Alignment B-H1 and VAX2

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_036608.1
• Gene: VAX2 / 25806
• HGNCID: 12661
• Length: 290
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 79/288 - (27%)
• Similarity: 113/288 - (39%)
• Gaps: 71/288 - (24%)

  Fly   231 DGGVDGGVGLAPPA-----GGDLDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTS 290
            |||.:...|.|..|     ||...|.|...:..  .|.|......|.........| |.:||:.|
Human     3 DGGAERDRGPARRAESGGGGGRCGDRSGAGDLR--ADGGGHSPTEVAGTSASSPAG-SRESGADS 64

  Fly   291 D----------------------------MSGLS-KKQRKARTAFTDHQLQTLEKSFERQKYLSV 326
            |                            ..||. .:.::.||:||..||..||..|:|.:|:..
Human    65 DGQPGPGEADHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVG 129

  Fly   327 QERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLE-----------------LLAEAGNFAAF 374
            :||.|||.:|:||:.|||.|:||||||.|:..:..||                 .|.|.|...:.
Human   130 RERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEAFATSNILRLLEQGRLLSV 194

  Fly   375 QR---LYGGSPYLGAWPYA---AAAGAAHGATPHTNIDIYYRQAAAAAAMQKPLPYNLYAGVPSV 433
            .|   |...:|.|...|.:   .:.|....::|..|   ....|:|:..:..|||...::..|.:
Human   195 PRAPSLLALTPSLPGLPASHRGTSLGDPRNSSPRLN---PLSSASASPPLPPPLPAVCFSSAPLL 256

  Fly   434 GVGVGVGVGPA---PFSHL-----SASS 453
            .:..|..:|.:   |:|.|     ||||
Human   257 DLPAGYELGSSAFEPYSWLERKVGSASS 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	29/55 (53%)
VAX2	NP_036608.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..75		19/74 (26%)
		Homeodomain	103..159	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	205..240		8/37 (22%)