DRSC/TRiP Functional Genomics Resources

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Protein Alignment B-H1 and GSX1

DIOPT Version :10

Sequence 1:NP_523387.1 Gene:B-H1 / 32724 FlyBaseID:FBgn0011758 Length:544 Species:Drosophila melanogaster
Sequence 2:NP_663632.1 Gene:GSX1 / 219409 HGNCID:20374 Length:264 Species:Homo sapiens


Alignment Length:247 Identity:71/247 - (28%)
Similarity:92/247 - (37%) Gaps:83/247 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   118 PAHSNNNNNINGDNCEASNVAGVGVLP-----SALHHPQPHPPTHPHTHPHALMHPHGKLGHFPP 177
            |.|:  .:.::...|.|.....:.|.|     |.||.| |.||..|      |:.     ..|||
Human    35 PPHA--LHGLSPGACHARKAGLLCVCPLCVTASQLHGP-PGPPALP------LLK-----ASFPP 85

  Fly   178 TAGGNGLNVAQYAAAM--QQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGL 240
            ..       :||..|.  :||.|.:...      |...||||||||....:.|            
Human    86 FG-------SQYCHAPLGRQHSAVSPGV------AHGPAAAAAAAALYQTSYP------------ 125

  Fly   241 APPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMSGLSKKQRKARTA 305
                   |.|...:|     |.|             .|...|.:.|            .::.|||
Human   126 -------LPDPRQFH-----CIS-------------VDSSSNQLPS------------SKRMRTA 153

  Fly   306 FTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQ 357
            ||..||..||:.|....|||...|.|:|..|:||:.|||.|:||||.|.|::
Human   154 FTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKE 205

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
B-H1NP_523387.1 Homeodomain 300..356 CDD:459649 28/55 (51%)
GSX1NP_663632.1 SNAG domain. /evidence=ECO:0000250 1..20
Homeodomain 148..204 CDD:459649 28/55 (51%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 201..264 2/5 (40%)
Blue background indicates that the domain is not in the aligned region.

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