Protein Alignment B-H1 and EVX1

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001980.1
• Gene: EVX1 / 2128
• HGNCID: 3506
• Length: 407
• Species: Homo sapiens
• Alignment Length: 436
• Identity: 122/436 - (27%)
• Similarity: 158/436 - (36%)
• Gaps: 141/436 - (32%)

  Fly   130 DNCEASNVAG--VGVLPSALHHPQPHPPTHPHTHPHALMHPHGKLG--HFPPTA---GGNGLNVA 187
            |..:...:.|  |..|..|:..|.|.||..        |.|.|.|.  ..||..   ||.|
Human    12 DGGQLGTLVGKRVSNLSEAVGSPLPEPPEK--------MVPRGCLSPRAVPPATRERGGGG---- 64

  Fly   188 QYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSS 252
                  .:.......|.:|....|....|.||....|..||    .||...|...|:..|.:  |
Human    65 ------PEEEPVDGLAGSAAGPGAEPQVAGAAMLGPGPPAP----SVDSLSGQGQPSSSDTE--S 117

  Fly   253 DYHEENE-----DCDSGNMD-DHSVCS---------NGGKD---DDGNSVKSGSTSDMS-GLSKK 298
            |::||.|     ||.:||.: .||..|         |||.:   .:|.|...||...:: ..|.:
Human   118 DFYEEIEVSCTPDCATGNAEYQHSKGSGSEALVGSPNGGSETPKSNGGSGGGGSQGTLACSASDQ 182

  Fly   299 QRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLE 363
            .|:.|||||..|:..|||.|.|:.|:|...|.|||..|:|.:..:|.|:||||.|.||
Human   183 MRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKR------- 240

  Fly   364 LLAEAGNFAAFQRLYGGSPYLGAWPYAAAAGAAHGATP--HTNIDIYYRQAAAAAAMQKPLPYNL 426
                       |||      ...||        |.|.|  :|     |..:.||||...|.|:..
Human   241 -----------QRL------AMTWP--------HPADPAFYT-----YMMSHAAAAGGLPYPFPS 275

  Fly   427 YAGVPSVG-VGVGVGVGPAPFSHLSASSSLSSLSSYYQSAAAAASAANPGGPHPVAPPPSVGGGS 490
            :..:|... ||:|                          ||:|||||                .|
Human   276 HLPLPYYSPVGLG--------------------------AASAASAA----------------AS 298

  Fly   491 PPSGLVKPIPAHSASASPPPR---------PPSTPSPTLNPGSPPG 527
            |.||.::|:......:.|.||         ||..|.|....|:..|
Human   299 PFSGSLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLGASAG 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	27/55 (49%)
EVX1	NP_001980.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..120		30/114 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..179		10/41 (24%)
		Homeodomain	184..240	CDD:459649	27/55 (49%)