Protein Alignment B-H1 and EMX2

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_004089.1
• Gene: EMX2 / 2018
• HGNCID: 3341
• Length: 252
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 81/309 - (26%)
• Similarity: 111/309 - (35%)
• Gaps: 110/309 - (35%)

  Fly   112 SSGGSSPAHSNNNNNINGDNCEASNVAGVGV--------LPSALHHPQPHPPTHPHTHPHAL-MH 167
            |...|||.    |..:||.:..|:..||.||        ..:..|.|.|..|.||...|||| .|
Human    37 SYANSSPI----NPFLNGFHSAAAAAAGRGVYSNPDLVFAEAVSHPPNPAVPVHPVPPPHALAAH 97

  Fly   168 PHGKLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDG 232
            |      .|.:...:.|      .|.||.
Human    98 P------LPSSHSPHPL------FASQQR------------------------------------ 114

  Fly   233 GVDGGVGLAPPAGGDLDDSSDY----HEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMS 293
                            |.|:.|    |...               ..|....||.....|....:
Human   115 ----------------DPSTFYPWLIHRYR---------------YLGHRFQGNDTSPESFLLHN 148

  Fly   294 GLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQT 358
            .|::|.::.||||:..||..||.:||:..|:...||::|||.|.|::.|||.|:||||||:|||.
Human   149 ALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQK 213

  Fly   359 AVGLELLAEAGNFAAFQRLYGGSPYLGAWPYAAAAGAAHGATPHTNIDI 407
                  |.|.|:.:  |:...|:.::..|..|...     |:|. .||:
Human   214 ------LEEEGSDS--QQKKKGTHHINRWRIATKQ-----ASPE-EIDV 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	28/55 (51%)
EMX2	NP_004089.1	Homeodomain	155..211	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..252		12/51 (24%)