Protein Alignment B-H1 and EMX1

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_004088.2
• Gene: EMX1 / 2016
• HGNCID: 3340
• Length: 290
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 86/293 - (29%)
• Similarity: 116/293 - (39%)
• Gaps: 73/293 - (24%)

  Fly   139 GVGVLPSALHHPQPHPPTHPHTHPHA--LMHPHGKLGHF--------PPTAGGNGLNVAQYAAAM 193
            |.|.||.|         ..|.|.|.|  :..|..|.|..        ..|.||.|      ....
Human    15 GRGALPRA---------RLPRTAPAAATMFQPAAKRGFTIESLVAKDGGTGGGTG------GGGA 64

  Fly   194 QQHYAAAAAA-----AAARNNAAAAAAAAA------AAAAAGVAAPPVDGGVDGGVGLAPPAGGD 247
            ..|..||||:     ..|.|....:||.||      ||||||...     .:.||..|..|...:
Human    65 GSHLLAAAASEEPLRPTALNYPHPSAAEAAFVSGFPAAAAAGAGR-----SLYGGPELVFPEAMN 124

  Fly   248 LDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDD--------------GNSVKSGSTSDMSGL--- 295
             ..:...|..::...|.....||..  |.:..|              |:..:: |.....||
Human   125 -HPALTVHPAHQLGASPLQPPHSFF--GAQHRDPLHFYPWVLRNRFFGHRFQA-SDVPQDGLLLH 185

  Fly   296 ---SKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQ 357
               ::|.::.||||:..||..||::||:..|:...||::||..|.||:.|||.|:||||||:|||
Human   186 GPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQ 250

  Fly   358 TAVGLELLAEAGNFAAFQRLYGGSPYLGAWPYA 390
            .      |.|.|  ...::...||.::..|..|
Human   251 K------LEEEG--PESEQKKKGSHHINRWRIA 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	28/55 (51%)
EMX1	NP_004088.2	Homeodomain	193..249	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..290		9/35 (26%)