DRSC/TRiP Functional Genomics Resources

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Protein Alignment B-H1 and Npm1

DIOPT Version :9

Sequence 1:NP_523387.1 Gene:B-H1 / 32724 FlyBaseID:FBgn0011758 Length:544 Species:Drosophila melanogaster
Sequence 2:NP_032748.1 Gene:Npm1 / 18148 MGIID:106184 Length:292 Species:Mus musculus


Alignment Length:104 Identity:27/104 - (25%)
Similarity:41/104 - (39%) Gaps:25/104 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   243 PAGGD--------LDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMSGLSKKQ 299
            |.||:        ||      |::||.|..:.||        :|||.:......|.:...:.|..
Mouse   145 PGGGNKVPQKKVKLD------EDDEDDDEDDEDD--------EDDDDDDFDEEETEEKVPVKKSV 195

  Fly   300 R--KARTAFTDHQL-QTLEKSFERQKYLSVQERQELAHK 335
            |  .|:.|...:|. :.|:.|..|.|.....::||...|
Mouse   196 RDTPAKNAQKSNQNGKDLKPSTPRSKGQESFKKQEKTPK 234

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
B-H1NP_523387.1 Homeobox 303..355 CDD:278475 9/34 (26%)
Npm1NP_032748.1 Required for interaction with SENP3. /evidence=ECO:0000250 1..185 14/53 (26%)
Necessary for interaction with APEX1. /evidence=ECO:0000250 1..117
Nucleoplasmin 18..116 CDD:308605
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 138..248 27/104 (26%)
Nuclear localization signal. /evidence=ECO:0000255 152..157 0/4 (0%)
Nuclear localization signal. /evidence=ECO:0000255 190..196 1/5 (20%)
Required for nucleolar localization. /evidence=ECO:0000250 241..292
NPM1-C 243..291 CDD:318505
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0488
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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