Protein Alignment B-H1 and Nkx2-5

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_032726.1
• Gene: Nkx2-5 / 18091
• MGIID: 97350
• Length: 318
• Species: Mus musculus
• Alignment Length: 370
• Identity: 94/370 - (25%)
• Similarity: 133/370 - (35%)
• Gaps: 118/370 - (31%)

  Fly   194 QQHYAAAAAAAAARNNAAAAAAAA--AA----------AAAAGVA----------APP-VDGGVD 235
            ||..:.|:...:||..|..|.|:.  ||          |||:|:|          :|| ......
Mouse    22 QQQRSLASGDLSARLEATLAPASCMLAAFKPEAYSGPEAAASGLAELRAEMGPAPSPPKCSPAFP 86

  Fly   236 GGVGLAPPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMSGLSKKQR 300
            ......|.|.||.|.:.|          ...|...:|:.....:...:...|:....   ::::|
Mouse    87 AAPTFYPGAYGDPDPAKD----------PRADKKELCALQKAVELDKAETDGAERPR---ARRRR 138

  Fly   301 KARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTA-VGLEL 364
            |.|..|:..|:..||:.|::|:|||..||.:||..|.|:..|||.|:||||.|.|||.. ..|||
Mouse   139 KPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQDQTLEL 203

  Fly   365 LA----EAGNFAAFQRLYGGSPYLGAWPYAAAAGAAHGATPHTNIDIYYRQAAAAAAMQKPLPYN 425
            |.    .|...|....:..|.|.||                                  .|..|
Mouse   204 LGPPPPPARRIAVPVLVRDGKPCLG----------------------------------DPAAY- 233

  Fly   426 LYAGVPSVGVGV---GVGVGPAPFSHLSASSSLSSLSSYYQSAAAAASAANPG---GPHPVAPPP 484
                .|:.|||:   |....|.|              ||      ..:|.:||   ..:|.|||.
Mouse   234 ----APAYGVGLNAYGYNAYPYP--------------SY------GGAACSPGYSCAAYPAAPPA 274

  Fly   485 SVGGGSPPSGLVKPIPAHSASASPPPRPPSTPSPTLNPGSPPGRS 529
            :           :| ||.||:::.........:...:||.|.|.|
Mouse   275 A-----------QP-PAASANSNFVNFGVGDLNTVQSPGMPQGNS 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	27/55 (49%)
Nkx2-5	NP_032726.1	Homeodomain	144..194	CDD:459649	24/49 (49%)