Protein Alignment B-H1 and DLX3

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_005211.1
• Gene: DLX3 / 1747
• HGNCID: 2916
• Length: 287
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 70/238 - (29%)
• Similarity: 100/238 - (42%)
• Gaps: 66/238 - (27%)

  Fly   280 DGNSVKSGSTSD---MSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDC 341
            |..|||....::   ::|..||.||.||.::.:||..|::.|::.:||::.||.|||.:|.|:..
Human   107 DPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQT 171

  Fly   342 QVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGSPYLGAWPYAAAAGAAHGATPHTNID 406
            |||.|:||||:|:|:....|...|..:.|.:  ..:...||     |..|....:..:||
Human   172 QVKIWFQNRRSKFKKLYKNGEVPLEHSPNNS--DSMACNSP-----PSPALWDTSSHSTP----- 224

  Fly   407 IYYRQAAAAAAMQKPLPYNLYAGVPSVGVGVGVGVGPAPFSHLSASSSL--SSLSSYYQSAAAAA 469
                 |.|.:.:..||||                         |||.|.  ...:|:|.
Human   225 -----APARSQLPPPLPY-------------------------SASPSYLDDPTNSWYH------ 253

  Fly   470 SAANPGGPHPVAPPPSVGGGSPPSGLVKPIPAHSASASPPPRP 512
             |.|..|||....||            :|...|.||..|||.|
Human   254 -AQNLSGPHLQQQPP------------QPATLHHASPGPPPNP 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	26/55 (47%)
DLX3	NP_005211.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..39
		DLL_N	27..107	CDD:463567	70/238 (29%)
		COG5576	<109..232	CDD:227863	44/139 (32%)
		homeobox	129..188		27/58 (47%)
		Homeodomain	130..186	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		35/150 (23%)