Protein Alignment B-H1 and DLX1

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_835221.2
• Gene: DLX1 / 1745
• HGNCID: 2914
• Length: 255
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 76/295 - (25%)
• Similarity: 119/295 - (40%)
• Gaps: 64/295 - (21%)

  Fly   143 LPSALHHP--------QPHPPTH-----PHTHPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQ 194
            :|.:|:.|        :..||..     |.:|.|..||.....||..|  .|...:.:.::..:.
Human     6 MPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQP--DGAYSSASSFSRPLG 68

  Fly   195 QHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENE 259
            ..|.          |:.::.|::           |....|....|.|..|...|:|.
Human    69 YPYV----------NSVSSHASS-----------PYISSVQSYPGSASLAQSRLEDP-------- 104

  Fly   260 DCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYL 324
                            |.|.:.::|..|.....:|..||.||.||.::..|||.|.:.|::.:||
Human   105 ----------------GADSEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYL 153

  Fly   325 SVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGSPYL-GAWP 388
            ::.||.|||..|.|:..|||.|:||:|:|:|:....|...| |....|..:.|..|||.: ..|.
Human   154 ALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAAL-EGSALANGRALSAGSPPVPPGWN 217

  Fly   389 YAAAAGAAHGATPHTNIDIY--YRQAAAAAAMQKP 421
            ..:::|...|....:.|..|  :..:|...|||:|
Human   218 PNSSSGKGSGGNAGSYIPSYTSWYPSAHQEAMQQP 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	26/55 (47%)
DLX1	NP_835221.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		6/31 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..118		7/46 (15%)
		Homeodomain	129..185	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..230		7/25 (28%)