Protein Alignment B-H1 and Hoxb3

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_034588.2
• Gene: Hoxb3 / 15410
• MGIID: 96184
• Length: 433
• Species: Mus musculus
• Alignment Length: 450
• Identity: 115/450 - (25%)
• Similarity: 155/450 - (34%)
• Gaps: 143/450 - (31%)

  Fly   112 SSGGSSPAHSNNNNNINGDNCEASNVAGVGVLPSALHHPQPHPPTHPHTHPHALM----HPHGKL 172
            |.|.::| |: .:..:|| :|...     |:.|..|..|...||  |...|.:..    :..|..
Mouse    56 SLGNAAP-HA-KSKELNG-SCMRP-----GLAPEPLPAPPGSPP--PSAAPTSTTSNSNNGGGPS 110

  Fly   173 GHFPPT--AGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVD 235
            ...||.  ||.|.....|....|::     :...:...|::...|........|       ||..
Mouse   111 KSGPPKCGAGSNSTLTKQIFPWMKE-----SRQTSKLKNSSPGTAEGCGGGGGG-------GGGG 163

  Fly   236 GGVGLAPPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMSGLSKKQR 300
            ||.|.....||                            ||....|:....||.:        .:
Mouse   164 GGGGGGSSGGG----------------------------GGGGGGGDKSPPGSAA--------SK 192

  Fly   301 KARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKR-QTAVGLEL 364
            :||||:|..||..|||.|...:||....|.|:|:.|:||:.|:|.|:||||.|:|: |.|.|  |
Mouse   193 RARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKG--L 255

  Fly   365 LAEAGNFAAFQRLYGGSPYLGAWPYAAAAG---AAHGATPHTNIDIYYRQAAAAAAMQKPLP--- 423
            .:.:|..:.     .|||   ..|..:.||   |.|..||               :...|.|
Mouse   256 ASSSGGPSP-----AGSP---PQPMQSTAGFMNALHSMTP---------------SYDSPSPPAF 297

  Fly   424 ----YNLYAGVPS------VGVGVGVGVGPAPFSHLSASSSLSSLSSYYQSAAAAASAANPGGPH 478
                .|.|| :||      .|.|......|.|             :|.|:.....|:....|.|.
Mouse   298 GKGHQNAYA-LPSNYQPPLKGCGAPQKYPPTP-------------ASEYEPHVLQANGGAYGTPT 348

  Fly   479 PVAPPPSVGGGSPPSGLVKPIPAHSASASPPPRPPST---------PSPTL--NPGSPPG 527
            ....|..||||    |...|:        |||..||.         ||..|  |..:|.|
Mouse   349 MQGSPVYVGGG----GYADPL--------PPPAGPSLYGLNHLSHHPSGNLDYNGAAPMG 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	27/55 (49%)
Hoxb3	NP_034588.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..124		18/69 (26%)
		Antp-type hexapeptide	129..134		0/4 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	136..195		15/101 (15%)
		Homeodomain	192..248	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..276		9/36 (25%)
		DUF4074	369..431	CDD:463833	7/27 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..433		2/7 (29%)