Protein Alignment B-H1 and Mnx1

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_064328.2
• Gene: Mnx1 / 15285
• MGIID: 109160
• Length: 404
• Species: Mus musculus
• Alignment Length: 509
• Identity: 133/509 - (26%)
• Similarity: 161/509 - (31%)
• Gaps: 180/509 - (35%)

  Fly    42 LQPPAVAHSIHSTTTMSSGGSTTTASGIGKPNRSRFMINDILAGSAAAAFYKQQQHHQQLHHHNN 106
            :.||..| |..|..........||.||.|:            .||.                 ..
Mouse    15 VDPPRAA-STQSAPLALVTSLATTVSGPGR------------GGSG-----------------GG 49

  Fly   107 NNNSGSSGGSSPAHSNNNNNINGDNCEASNVAGVGVLPSALHHPQPHPPTHPHTHPHALMHPHGK 171
            ..:||:|...|||.|           ||:...|     ..|....|.||.....| .||:...|.
Mouse    50 GTSSGASRSCSPASS-----------EATAAPG-----DRLRAESPSPPRLLAAH-CALLPKPGF 97

  Fly   172 LGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDG 236
            ||     |||.|  .|........|:|...|       |||||||||||||.|:|.....||..|
Mouse    98 LG-----AGGGG--GAAGGPGTPHHHAHPGA-------AAAAAAAAAAAAAGGLALGLHPGGAQG 148

  Fly   237 GVGLAPPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDDG-------NSVKSG------- 287
            |.||  ||...|.....|........:.....|...|.......|       :.:|.|
Mouse   149 GAGL--PAQAALYGHPVYSYSAAAAAAALAGQHPALSYSYPQVQGAHPAHPADPIKLGASTFQLD 211

  Fly   288 -----STSDM-------------SGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAH 334
                 ||:.|             |.|..|.|:.|||||..||..||..|:..||||..:|.|:|.
Mouse   212 QWLRASTAGMILPKMPDFSSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVAT 276

  Fly   335 KLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGSPYLGAWPYAAAAGAAHGA 399
            .|.|::.|||.|:||||.||||....
Mouse   277 SLMLTETQVKIWFQNRRMKWKRSKKA--------------------------------------- 302

  Fly   400 TPHTNIDIYYRQAAAAAAMQKPLPYNLYAGVPSVGVGVGVG----------VGPAPFSHLSASSS 454
                     ..|||..|..||           ..|.|.|.|          :||......::...
Mouse   303 ---------KEQAAQEAEKQK-----------GGGGGTGKGGSEEKTEEELMGPPVSGDKASGRR 347

  Fly   455 LSSLSSY---------------YQSAAAAASAANPGGPHPVAPPPSVGG-GSPP 492
            |..|...               |.:.|.|.:|::.......:|||.:|| |..|
Mouse   348 LRDLRDSDPDEDEDDEEEDNFPYSNGAGAHAASSDCSSEDDSPPPRLGGPGHQP 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	30/55 (55%)
Mnx1	NP_064328.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..80		18/88 (20%)
		Homeodomain	242..298	CDD:459649	30/55 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..404		25/162 (15%)