Protein Alignment B-H1 and En2

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_034264.1
• Gene: En2 / 13799
• MGIID: 95390
• Length: 324
• Species: Mus musculus
• Alignment Length: 320
• Identity: 83/320 - (25%)
• Similarity: 118/320 - (36%)
• Gaps: 73/320 - (22%)

  Fly   107 NNNSGSSGGSSPAHSNNNNNINGDNCEASNVAGVGVLPSALHHPQPHPPTHPHTHPHA------- 164
            ::..||.|||||:.|:....            ...:||..|..|      ..|.|||.
Mouse    22 SSGGGSGGGSSPSDSDTGRR------------RALMLPEVLQAP------GNHQHPHRITNFFID 68

  Fly   165 -LMHPH-------------------GKLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNN 209
             ::.|.                   |:.|......||.|...|:.....::.....|.|.:|...
Mouse    69 NILRPEFGRRKDAGTCCAGAGGARGGEGGAGTTEGGGGGAGGAEQLLGARESRPNPACAPSAGGT 133

  Fly   210 AAAAAAAAAAAAAAGV--------AAPPVD--GGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSG 264
            .:|||...|.....|.        |..|.|  |.:||.:......||||..|||..........|
Mouse   134 LSAAAGDPAVDGEGGSKTLSLHGGAKKPGDPGGSLDGVLKARGLGGGDLSVSSDSDSSQASATLG 198

  Fly   265 NM----DDHSVCSNGGKDDDGNSVKSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLS 325
            ..    .....|:.  ..|..:|............:|:.::.|||||..|||.|:..|:..:||:
Mouse   199 AQPMLWPAWVYCTR--YSDRPSSGPRSRKPKKKNPNKEDKRPRTAFTAEQLQRLKAEFQTNRYLT 261

  Fly   326 VQERQELAHKLDLSDCQVKTWYQNRRTKWKRQT----AVGLELLAEAGNFAAFQRLYGGS 381
            .|.||.||.:|.|::.|:|.|:||:|.|.|:.|    .:.:.|:|        |.||..|
Mouse   262 EQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMA--------QGLYNHS 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	26/55 (47%)
En2	NP_034264.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..59		13/54 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..174		20/84 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	215..240		3/24 (13%)
		Homeodomain	236..292	CDD:459649	26/55 (47%)
		Engrail_1_C_sig	293..323	CDD:431338	7/29 (24%)