Protein Alignment B-H1 and Nkx3-2

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_031550.2
• Gene: Nkx3-2 / 12020
• MGIID: 108015
• Length: 333
• Species: Mus musculus
• Alignment Length: 260
• Identity: 70/260 - (26%)
• Similarity: 100/260 - (38%)
• Gaps: 68/260 - (26%)

  Fly   165 LMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQHY---AAAAAAAAARNNAAAAAAAAAAAAAAGVA 226
            |..|.|:     |..||..:.|....|......   ..|.|...|.::..|:.|....|......
Mouse    27 LATPEGR-----PAPGGTEVAVTAAPAVCCWRIFGETEAGALGGAEDSLLASPARTRTAVGQSAE 86

  Fly   227 APPVDGGVDGGVGLA------------PPAGG---------------DLDDSSDYHEE-----NE 259
            :|   ||.|....|:            |.|.|               :|..:.|..||     :.
Mouse    87 SP---GGWDSDSALSEENEGRRRCADVPGASGTGRARVTLGLDQPGCELHAAKDLEEEAPVRSDS 148

  Fly   260 DCDSGNMDDHSVCSNGGKDDD-----------GNSVKSGSTSDMSG--------LSKKQRK--AR 303
            :..:....||   |..|:||.           ..:..||::...:|        .:.|.||  :|
Mouse   149 EMSASVSGDH---SPRGEDDSVSPGGARVPGLRGAAGSGASGGQAGGVEEEEEPAAPKPRKKRSR 210

  Fly   304 TAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEA 368
            .||:..|:..||:.|..|:|||..||.:||..|.|::.|||.|:||||.|.||: .:..:|||.|
Mouse   211 AAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRR-QMAADLLASA 274

  Fly   369  368
            Mouse   275  274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	28/57 (49%)
Nkx3-2	NP_031550.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	74..121		10/49 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..212		16/77 (21%)
		Homeodomain	207..263	CDD:459649	26/55 (47%)