Protein Alignment B-H1 and VAX1

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001106175.1
• Gene: VAX1 / 11023
• HGNCID: 12660
• Length: 334
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 87/308 - (28%)
• Similarity: 121/308 - (39%)
• Gaps: 99/308 - (32%)

  Fly   251 SSDYHEENEDCD--SGNM------DDHSVCSNGGKDDDGNSVKSGSTSD---------------- 291
            |.:.|:|:.:..  .||:      :.....|..|..:|.|..||.|.:|
Human    22 SKNAHKESRESKGAEGNLPAAFLKEPQGAFSASGAAEDCNKSKSNSAADPDYCRRILVRDAKGSI 86

  Fly   292 -----MSGLS-KKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNR 350
                 ..||. .:.::.||:||..||..||..|:|.:|:..:||.|||.:|:||:.|||.|:|||
Human    87 REIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNR 151

  Fly   351 RTKWKRQTAVGLELLAEAGNFAA----FQRLYGG----SPYLGAWPYAAAAGAAHGATPHTNIDI 407
            |||.|:......||.:.....||    .:.|..|    .|.|.|.....|.|
Human   152 RTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATG------------- 203

  Fly   408 YYRQAAAAAAMQKPLPYNLYAGVPSVGVGVGVGVGPAPFSHLSASSSLSSLSSYYQSAAAAASAA 472
                 |..:|::.|       .:|::|.|...|                      .:|||||:|.
Human   204 -----ALGSALRGP-------SLPALGAGAAAG----------------------SAAAAAAAAP 234

  Fly   473 NPGG---PHPVAPPPSVGGG-----SPPSGLVKPIPA--HSASASPPP 510
            .|.|   ||    ||:|||.     :.|.||....||  ||..:.|.|
Human   235 GPAGAASPH----PPAVGGAPGPGPAGPGGLHAGAPAAGHSLFSLPVP 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	29/55 (53%)
VAX1	NP_001106175.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41		5/18 (28%)
		COG5576	66..184	CDD:227863	39/117 (33%)
		Homeodomain	101..157	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	234..263		12/32 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	314..334