Protein Alignment B-H1 and en2

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_002932525.1
• Gene: en2 / 100498251
• XenbaseID: XB-GENE-853108
• Length: 266
• Species: Xenopus tropicalis
• Alignment Length: 304
• Identity: 75/304 - (24%)
• Similarity: 112/304 - (36%)
• Gaps: 96/304 - (31%)

  Fly   122 NNNNNINGDNCEASNVAGVGVLPSALHHPQPHPPTHPHTHPHALMHPHGKLGHF------PPTAG 180
            |..||...:..|:.:.:..|:|     |..|     |..|     .||.::.:|      .|..|
 Frog     4 NEQNNREVEPQESGDESNRGIL-----HQAP-----PGNH-----QPHHRITNFFIDNILRPEFG 53

  Fly   181 GNGLNVA---QYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAP 242
            .....::   :..:.......:.|.:|..|.||...|..:.|....|
 Frog    54 RRKEGISHQDELFSGRDSGALSGAESAHHRANATEGAGGSKAITLTG------------------ 100

  Fly   243 PAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDM--------------- 292
                  |..||...|......|:..|||:.|     |..:|..|..||..
 Frog   101 ------DKKSDIAMEESLKSRGHNGDHSLSS-----DSDSSQASSKTSQQPMLWPAWVYCTRYSD 154

  Fly   293 ---SG-------------LSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDC 341
               ||             ::|:.::.|||||..|||.|:..|:..:||:.|.||.||.:|.|::.
 Frog   155 RPSSGPRSRKPKKKTTTTVTKEDKRPRTAFTADQLQRLKAEFQTNRYLTEQRRQSLAQELSLNES 219

  Fly   342 QVKTWYQNRRTKWKRQT----AVGLELLAEAGNFAAFQRLYGGS 381
            |:|.|:||:|.|.|:.|    ::.|.|:|        |.||..|
 Frog   220 QIKIWFQNKRAKIKKATGNKNSLALHLMA--------QGLYNHS 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	26/55 (47%)
en2	XP_002932525.1	Homeodomain	178..234	CDD:459649	26/55 (47%)
		Engrail_1_C_sig	235..265	CDD:431338	8/29 (28%)