Protein Alignment B-H1 and nkx1-1

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_002936812.1
• Gene: nkx1-1 / 100493120
• XenbaseID: XB-GENE-488879
• Length: 408
• Species: Xenopus tropicalis
• Alignment Length: 502
• Identity: 110/502 - (21%)
• Similarity: 154/502 - (30%)
• Gaps: 171/502 - (34%)

  Fly    74 RSRFMINDILAGSAAAAFYKQQQ---HHQQLHHHNNNNNSGSSGGSSPAHSNNNNNINGD--NCE 133
            |.:..::..:.|:.||...:...   |.:.:..|.....:.|   ..||:....:. .||  ||.
 Frog     5 REKVQLDMPIGGAQAAGVVEAVTCGLHGEMMDSHGEQRLTAS---DLPAYGCPRDR-QGDHPNCN 65

  Fly   134 A-SNVAGVGVLPSALHHP---------QPHPPTHPHTHPHALMHPHG-------KLGHFPPTAGG 181
            | :....:|..|.|:|..         .|:.......|......|.|       :....|..|.|
 Frog    66 APAGPESLGAAPLAVHRTTSFSVLDILDPNKFNSKQRHCSGAYKPPGDYILRGEEKAEGPDIATG 130

  Fly   182 NGLNVAQYAA-----------AMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVD 235
            ....:.:|.:           .:.||.|........
 Frog   131 QKAFLEEYESCKKSTEVIKEEGLYQHSATEDCQTQE----------------------------- 166

  Fly   236 GGVGLAPPAGGDLDDSSDYHEENEDCD--------SGNMDDHSVCSNG-GKDDDGNSVKSGSTSD 291
                .:|..|.||::..|..|:.|.|.        ||..:......|| |:|.......:||...
 Frog   167 ----FSPSPGSDLEEEEDEEEDEEICSEESSNSTPSGLAERDPGAGNGQGEDALNTGAPAGSNQQ 227

  Fly   292 M----------------------SGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAH 334
            .                      ...|.|.|:||||||..||..||..|:..:||||.||..||.
 Frog   228 QPTGKNQQQQNQHGKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKSTRYLSVCERLNLAL 292

  Fly   335 KLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGSPYLGAWPYAAAAGAAHGA 399
            .|.|::.|||.|:||||||||:|..                         ||...|...|:.||.
 Frog   293 SLSLTETQVKIWFQNRRTKWKKQNP-------------------------GADTSAPTGGSGHGG 332

  Fly   400 TPHTNIDIYYRQAAAAAAMQKPLPYNLYAGVPSVGVGVGVGVGPAPFSHLSASSSLSSLSSY--Y 462
            .                                 |.|..:|.|.:|.||.....:..:|..:  |
 Frog   333 G---------------------------------GSGSVLGGGLSPLSHSPPMGNPMALHGHHGY 364

  Fly   463 QSAAAAASAANPGGPHPVAPPPSVGGGSPPSGLVKPIPAHSASASPP 509
            .|.|       |||....|..|.:.|   |:.::.|....|.|...|
 Frog   365 PSHA-------PGGLMCTAQLPFLPG---PAAVLSPFVLSSQSYGAP 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	33/55 (60%)
nkx1-1	XP_002936812.1	Homeodomain	258..314	CDD:459649	33/55 (60%)