Protein Alignment B-H2 and Barhl2

DIOPT Version :10

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_075245.1
• Gene: Barhl2 / 65050
• RGDID: 620726
• Length: 384
• Species: Rattus norvegicus
• Alignment Length: 535
• Identity: 154/535 - (28%)
• Similarity: 191/535 - (35%)
• Gaps: 217/535 - (40%)

  Fly    54 ATRSRFMITDILAGAAAAS-------------------AAAAAAAAALAAASSGGGRGSP---TD 96
            |:.|.|.|..||:||.:.|                   .:.|..:......:.|....||   |.
  Rat     7 ASGSSFGIDTILSGAGSGSPGMMNGDFRSLGEARTTDFRSQATPSPCSEIDTVGTAPSSPISVTL 71

  Fly    97 SEREQSLVA---QHHHHHQQQQQHHHHQQQQQQQQHQQAALQQYIVQQQQLLRFERERERERERE 158
            ...|..||.   ||||       |.||.||
  Rat    72 EPPEPHLVTDGPQHHH-------HLHHGQQ----------------------------------- 94

  Fly   159 HYRERHSPPGNNPYAHHPMPPHLLAHFPPAHYAVLQQQQQQQQQQQHPHPHHLQLERERLEALHR 223
                             |.||..    |||     |..|...|||..|.|.....:.....|..|
  Rat    95 -----------------PPPPSA----PPA-----QSLQPSPQQQPPPQPQSAAQQLGSAAAAPR 133

  Fly   224 HG------HGLTGDPAQHLSHLSHLSHQQHHPHLHHPMHD----ERSRSPLMLQQLGGNGGNNNN 278
            ..      ..:.|| ::.|:..:..|.....|| |.|..:    ..|..|.:.|:
  Rat   134 TSTSSFLIKDILGD-SKPLAACAPYSTSVSSPH-HTPKQECNAAHESFRPKLEQE---------- 186

  Fly   279 NNNNSSSASNNNNNNNNSASANSNIISGNSSSSNNNNGSGNGNMLLGGPGSSISGDQASTID--- 340
                                                                   |..:.:|
  Rat   187 -------------------------------------------------------DSKTKLDKRE 196

  Fly   341 DSDSD-DCGGKDDDGDDSMKNGSSANGDSSSHLSLSL-SKKQRKARTAFTDHQLQTLEKSFERQK 403
            ||.|| .|.|..::||..:         :||..|..: :||.|||||||:||||..||:||||||
  Rat   197 DSQSDIKCHGTKEEGDREI---------TSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQK 252

  Fly   404 YLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGATPYL-- 466
            ||||||||:||..|.|:|.||||||||||||||||||||||||||||||:|.||::  .:||.
  Rat   253 YLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF--PSPYFYH 315

  Fly   467 --------SAWPYAAAAAAQSPHGATPSAIDIYYRQAAAAAAMQKPSLPASYRMYQSSIPPG--- 520
                    |....|||||..|....||         .|....:|:|.:|   |:....:.||
  Rat   316 PSLLGSMDSTTAAAAAAAMYSSMYRTP---------PAPHPQLQRPLVP---RVLIHGLGPGGQP 368

  Fly   521 ------MSLPGMPAP 529
                  ..:||.|.|
  Rat   369 ALNPLSNPIPGTPHP 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	45/55 (82%)
Barhl2	NP_075245.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..134		40/194 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	154..237		29/157 (18%)
		Homeodomain	230..286	CDD:459649	45/55 (82%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..384		6/20 (30%)