Protein Alignment B-H2 and lbx2

DIOPT Version :9

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_001007135.1
• Gene: lbx2 / 64276
• ZFINID: ZDB-GENE-001206-2
• Length: 257
• Species: Danio rerio
• Alignment Length: 260
• Identity: 76/260 - (29%)
• Similarity: 110/260 - (42%)
• Gaps: 68/260 - (26%)

  Fly   257 DERSRSPLMLQQLGGNGGNNNNNNNNSSSASNNNNNNNNSASANS----NIISGNSSSSNNNNGS 317
            :||.|.|  |.||....  |:|......|..:..|..:...|..|    .::...:.||.:.||
Zfish    19 EERRRGP--LDQLPPPA--NSNKPLTPFSIEDILNKPSVKKSVGSLCPPRVLEKVTGSSASRNG- 78

  Fly   318 GNGNMLLGGPGS-----------SISGDQASTIDDSDSDDCGGKDDDGDDSMKNGSSANGDSSSH 371
                  :..|.|           :..|.:.|.|..::.              :...:|.|...:
Zfish    79 ------ISAPSSPLCALEELASKTFKGLEVSVIQAAEG--------------REHINAFGQRQA- 122

  Fly   372 LSLSLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWK 436
                 |||:||:|||||:||:..|||.|..|||||..||.::|.:|.|::.||.||:||||.|.|
Zfish   123 -----SKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLK 182

  Fly   437 RQTAVGLELLAEAGNY-----AAFQRL---------YGGA---TPYLSAWPYAAAAAAQSPHGAT 484
            |...   |:.|:..:.     .|.|:|         :||:   :|.||  |.|...:..|..|.|
Zfish   183 RDLE---EMKADVESLKKIPPQALQKLVSMEDMEDAHGGSGPISPSLS--PRAFPQSPSSSRGQT 242

  Fly   485  484
            Zfish   243  242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeobox	384..436	CDD:278475	30/51 (59%)
lbx2	NP_001007135.1	Required for convergent extension movement and hypaxial myogenesis during gastrulation. Required for the formation of thick and thin myofilaments. Required for myod1 expression in the pectoral fin bud. Required for continuous expression of cxcl12a in the posterior lateral mesoderm at the tail bud stage and in adaxial cells at the 10-somite stage. /evidence=ECO:0000269|PubMed:19216761, ECO:0000269|PubMed:22216300, ECO:0000269|PubMed:22406073	1..46		10/30 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43		9/27 (33%)
		Homeobox	129..183	CDD:395001	30/53 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..257		11/39 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810