DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment B-H2 and npm1b

DIOPT Version :9

Sequence 1:NP_523386.1 Gene:B-H2 / 32723 FlyBaseID:FBgn0004854 Length:645 Species:Drosophila melanogaster
Sequence 2:XP_005173145.2 Gene:npm1b / 553507 ZFINID:ZDB-GENE-080723-7 Length:316 Species:Danio rerio


Alignment Length:136 Identity:24/136 - (17%)
Similarity:59/136 - (43%) Gaps:34/136 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   516 SIPPGMSLPGMPAPPP------PGAAPM-LSGYYAAAAAAAASAGAQQQQQQPPAASRSPATSQS 573
            |:.|.:||.|....||      .|..|: :||.:..:...:.....::::               
Zfish    97 SVLPSLSLGGFEVTPPVSFRLQSGGGPVYISGQHFVSVKESDDEDEEEEE--------------- 146

  Fly   574 ANSEADCERTSSSSRQRLITPSPPLNPGSPPHRERINEEEDRERDEERDIERERERERERDEDDE 638
             |:.:..:|.|:.:..::           |..:.:::.:||.:.|::.|.:.:.:.:.|.|:|.:
Zfish   147 -NNTSPVKRPSNMTLAKV-----------PQKKLKMDSDEDEDSDDDDDDDDDDDDDEEEDDDKQ 199

  Fly   639 EELALE 644
            |:.|::
Zfish   200 EKPAVK 205

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
B-H2NP_523386.1 Homeobox 384..436 CDD:278475
npm1bXP_005173145.2 Nucleoplasmin 32..131 CDD:308605 11/33 (33%)
NPM1-C 265..313 CDD:318505
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0488
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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