DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment B-H2 and barhl1b

DIOPT Version :9

Sequence 1:	NP_523386.1	Gene:	B-H2 / 32723	FlyBaseID:	FBgn0004854	Length:	645	Species:	Drosophila melanogaster
Sequence 2:	NP_001018142.1	Gene:	barhl1b / 553186	ZFINID:	ZDB-GENE-060118-2	Length:	323	Species:	Danio rerio

Alignment Length:	312	Identity:	120/312 - (38%)
Similarity:	153/312 - (49%)	Gaps:	63/312 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 DPAQHLSH-LSHLSHQQHHPHLHHPMHDERSRSPLMLQQLGGNGGNNNNNNNNSSSASNNNNNNN 294
            |.||...| |::.||.||.| :..........|..:::.:
Zfish    64 DAAQRQGHPLAYASHLQHGP-ISAGSQPRTVASSFLIRDI------------------------- 102

  Fly   295 NSASANSNIISGNSSSSNNNNGSGNGNMLLGGPGSSISGDQASTIDDSDSDDCGGK-DDDGDDSM 358
               .|:...::..:..|:|    |......|...|.|:.|....|..:.|.|...| .::||..:
Zfish   103 ---LADCKPLAACAPYSSN----GQPTQEAGRLASKIADDLIEKIHSNSSSDSEYKVKEEGDREI 160

  Fly   359 KNGSSANGDSSSHLSLSLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQ 423
               ||:.......|     ||.||||||||||||..||:|||||||||||||||||..|.|:|.|
Zfish   161 ---SSSRDSPQVRL-----KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQ 217

  Fly   424 VKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGATPYLSAWPYAAAAAAQSPHGATPSAI 488
            |||||||||||||||||||||||||||||:|.||::  .:||.    |..:..:....||   |:
Zfish   218 VKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF--PSPYF----YPQSLVSNLDPGA---AL 273

  Fly   489 DIYYRQAAAAAAMQKPSLPASYRMYQSSIPPGMSLPGMPAPPPPGAAPMLSG 540
            .:|...:|...|:|:|.:|   |:...      .|.|...||||  .|.|||
Zfish   274 YLYRGPSAPPPALQRPLVP---RILLH------GLQGASEPPPP--LPPLSG 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeobox	384..436	CDD:278475	43/51 (84%)
barhl1b	NP_001018142.1	Oxidoreductase_nitrogenase	48..>88	CDD:295466	10/24 (42%)
barhl1b	NP_001018142.1	Homeobox	178..230	CDD:278475	43/51 (84%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575741
Domainoid	1	1.000	103	1.000	Domainoid score	I6717
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	152	1.000	Inparanoid score	I4314
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002353
OrthoInspector	1	1.000	-	-		mtm6505
orthoMCL	1	0.900	-	-		OOG6_114730
Panther	1	1.100	-	-	O	PTHR24330
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10747
SonicParanoid	1	1.000	-	-		X1387
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.780