DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment B-H2 and barhl1a

DIOPT Version :9

Sequence 1:	NP_523386.1	Gene:	B-H2 / 32723	FlyBaseID:	FBgn0004854	Length:	645	Species:	Drosophila melanogaster
Sequence 2:	NP_001017712.2	Gene:	barhl1a / 550407	ZFINID:	ZDB-GENE-050417-212	Length:	299	Species:	Danio rerio

Alignment Length:	217	Identity:	96/217 - (44%)
Similarity:	115/217 - (52%)	Gaps:	57/217 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   330 SISGDQASTIDDSDSDDCGGK-----DDDGDDSMKNGSSANGDSSSHLSLSLSKKQRKARTAFTD 389
            |.:|..|     .|::||..|     ..|.:..:|:.:.....||.....|..||.|||||||||
Zfish   105 SSTGQSA-----QDAEDCMDKLHSNSSSDSEYRVKDEADREISSSRDSPNSRLKKPRKARTAFTD 164

  Fly   390 HQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAA 454
            |||..||:|||||||||||||||||..|.|:|.||||||||||||||||||||||||||||||:|
Zfish   165 HQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSA 229

  Fly   455 FQRLYGGATPYLSAWPYAAAAAAQSPHGATPSAIDIYYRQAAAAAAMQKPSLPASYRMYQSSIPP 519
            .||::  .:||                         :|.|:..                 |::.|
Zfish   230 LQRMF--PSPY-------------------------FYPQSLV-----------------SNLDP 250

  Fly   520 GMSL---PGMPAPPPPGAAPML 538
            |..|   .|..|||||...|::
Zfish   251 GPGLYLYRGPSAPPPPVQRPLV 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeobox	384..436	CDD:278475	43/51 (84%)
barhl1a	NP_001017712.2	TPP_enzymes	<122..177	CDD:294952	24/54 (44%)
barhl1a	NP_001017712.2	Homeobox	159..211	CDD:278475	43/51 (84%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575740
Domainoid	1	1.000	103	1.000	Domainoid score	I6717
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	152	1.000	Inparanoid score	I4314
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002353
OrthoInspector	1	1.000	-	-		mtm6505
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24330
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10747
SonicParanoid	1	1.000	-	-		X1387
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.880