Protein Alignment B-H2 and Tlx1

DIOPT Version :10

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_001102636.1
• Gene: Tlx1 / 499361
• RGDID: 1563655
• Length: 333
• Species: Rattus norvegicus
• Alignment Length: 314
• Identity: 83/314 - (26%)
• Similarity: 106/314 - (33%)
• Gaps: 121/314 - (38%)

  Fly   239 LSHLSHQQHHPHLHHPMH--------DERSRSP---------LMLQQ----LG---------GNG 273
            :.||.     ||..||.|        |:...||         ..||.    ||         |.|
  Rat     1 MEHLG-----PHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG 60

  Fly   274 GNNNNNNNNSSSASNNNNNNNNSASANSNIISGNSSSSNNNNGSGNGNM-LLGGPGSSISGDQAS 337
            |:........:.|............|..   .|.:.|.....||.|.|| |.||||....|
  Rat    61 GSAAGAGAGGTGAYGTGGPGGPGGPAGG---GGGACSMGPLAGSYNVNMALAGGPGPGGGG---- 118

  Fly   338 TIDDSDSDDCGGKDDDGDDSMKNGSSANG-----------DSSSH---LSLSL------------ 376
                      ||....|..::    ||.|           .:.:|   |:..|
  Rat   119 ----------GGAGAGGAGAL----SAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAVPGV 169

  Fly   377 -------------------------------SKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDR 410
                                           ..|::|.||:||..|:..|||.|.|||||:..:|
  Rat   170 NNLTGLTFPWMESNRRYTKDRFTGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAER 234

  Fly   411 MELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGN-------YAAFQR 457
            ..||..|:::|.|||||:|||||||:||||...|...:..|       ..|||:
  Rat   235 AALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQK 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	32/55 (58%)
Tlx1	NP_001102636.1	Homeodomain	205..261	CDD:459649	32/55 (58%)