Protein Alignment B-H2 and DBX2

DIOPT Version :10

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_001004329.2
• Gene: DBX2 / 440097
• HGNCID: 33186
• Length: 339
• Species: Homo sapiens
• Alignment Length: 219
• Identity: 61/219 - (27%)
• Similarity: 88/219 - (40%)
• Gaps: 49/219 - (22%)

  Fly   347 CGGKDDDGDDSMKNGSSANGDSSSHLSLSL-----SKKQRKA---RTAFTDHQLQTLEKSFERQK 403
            |||       |.:..:|:.........|.|     :.|.|:.   |..|::.|.:.|||.|::||
Human   152 CGG-------SCRRPASSTAFPREESMLPLLTQDSNSKARRGILRRAVFSEDQRKALEKMFQKQK 209

  Fly   404 YLSVQDRMELANKLELSDCQVKTWYQNRRTKW---KRQTAVGLELLAEAGNYAAFQRLYGGATPY 465
            |:|..||.:||..|.|.:.|||.|:||||.||   |.:..:....:.|.|
Human   210 YISKTDRKKLAINLGLKESQVKIWFQNRRMKWRNSKEKEVLSNRCIQEVG--------------- 259

  Fly   466 LSAWPYAAAAAA-QSPHGATPSAIDIYYRQAAAAAAMQKPSLPASYRMYQSSIPPGMSLPGMPAP 529
            |...|.:.:|.. .||   .||..|:  .|..::...::.|...|.|:.|.|          ...
Human   260 LQEDPLSRSALGFPSP---CPSIWDV--PQQHSSPRWRENSPEPSERLIQES----------SGA 309

  Fly   530 PPPGAAPMLSGYYAAAAAAAASAG 553
            |||.|..:....|..:...|.|.|
Human   310 PPPEANSLQGALYLCSEEEAGSKG 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	28/61 (46%)
DBX2	NP_001004329.2	PRK12323	<3..>146	CDD:481241
		Homeodomain	189..243	CDD:459649	27/53 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	282..318		10/47 (21%)