Protein Alignment B-H2 and MEOX2

DIOPT Version :10

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_005915.2
• Gene: MEOX2 / 4223
• HGNCID: 7014
• Length: 304
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 62/214 - (28%)
• Similarity: 97/214 - (45%)
• Gaps: 40/214 - (18%)

  Fly   233 AQHLSHLSHLSHQQHHPHLHHPMHDERSRSPLM----LQQLGGNGGNNNNNNNNSSSASNN---- 289
            :||     |..|..||.|.||..|.::....|.    |.|:          ::..|:|.::
Human    62 SQH-----HRGHHHHHHHHHHHHHQQQQHQALQTNWHLPQM----------SSPPSAARHSLCLQ 111

  Fly   290 -NNNNNNSASANSNIISGNSSSSNNNNGSGNGNMLLGGPGSSISGDQASTIDDSDSDDCGGKDDD 353
             ::.......::..::..||||..::..:|    ....||.  .|.||.:..:::....|.:..|
Human   112 PDSGGPPELGSSPPVLCSNSSSLGSSTPTG----AACAPGD--YGRQALSPAEAEKRSGGKRKSD 170

  Fly   354 GDDSMKNGSSANGDSSSHLSLSLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLE 418
            ..||.:      |:..|    .::.|.||.|||||..|::.||..|....||:...|.|:|..|:
Human   171 SSDSQE------GNYKS----EVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLD 225

  Fly   419 LSDCQVKTWYQNRRTKWKR 437
            |::.|||.|:||||.||||
Human   226 LTERQVKVWFQNRRMKWKR 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	28/55 (51%)
MEOX2	NP_005915.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..192		34/159 (21%)
		COG5576	160..284	CDD:227863	37/95 (39%)
		Homeodomain	188..244	CDD:459649	28/55 (51%)