Protein Alignment B-H2 and NK7.1

DIOPT Version :10

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Alignment Length: 760
• Identity: 163/760 - (21%)
• Similarity: 255/760 - (33%)
• Gaps: 275/760 - (36%)

  Fly    79 AAALAAASSGGGRGSPTDSEREQSLVAQHHHHHQQQQQHHHHQQQQQQQQHQQAALQQYIV---- 139
            ||.:|:.:.....|...|.:::|....|.||    .||.|||||||||||.||:....|.:
  Fly    13 AAEMASGALAHNYGIVKDQQQQQQQQQQLHH----LQQQHHHQQQQQQQQQQQSNSDLYKMACNG 73

  Fly   140 ------------------------QQQQLLRFEREREREREREHYRERHSPP------------G 168
                                    .:::|:...|.|:.........:  |||            .
  Fly    74 YNYSSPLTIPPTSMTTHMVSPIGNSKEKLVNMLRVRDNNNMASTISD--SPPTTFLQKQLEAVVA 136

  Fly   169 NNPYAHHPMPPHLLAHFPPAHYAVLQQQQQQQQQQQ----------------------------H 205
            ..|.:.||.      |..|      |||..|.|||:                            |
  Fly   137 PRPSSVHPQ------HQQP------QQQTVQLQQQRRSVSTPAITTTPGPPTNWHAHVYDRLPPH 189

  Fly   206 PHPHHLQ-------LERERLE-ALHRHGHGLTGDPAQH-LSHLSHLSHQQHHPHLHHPMHDER-S 260
            |.||.:.       :::||.| |....|      ||:. .|.|.....||       |:.... |
  Fly   190 PTPHSIADILGMSFVKKERPEVAFDAQG------PAKSPNSILKPYQEQQ-------PIRSSSIS 241

  Fly   261 RSPLMLQQLGGNGGNNNNNNNNSSSA-----------------------SNNNNNNNNSASANSN 302
            .|....::.....|..:.....::.|                       |.::||:...|:..|.
  Fly   242 MSDASEEESAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQ 306

  Fly   303 IISGNSSSSNNNNG---------------------SGNGNMLL---------GGPGSSISGDQAS 337
            |: |.|::...::|                     :|:.:.|:         ..|||:::....|
  Fly   307 IL-GKSATKKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQMQS 370

  Fly   338 --------TIDDSDSDDCGGKDDDGDDSMKNGSSANGDSSSHLSLSLSKKQRKARTAFTDHQLQT 394
                    |.|||||    |..|                        :::::||||.||..|:..
  Fly   371 NANSTLETTEDDSDS----GSTD------------------------ARRKKKARTTFTGRQIFE 407

  Fly   395 LEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLY 459
            |||.||.:||||..:|.|:|..|.:::.|||.|:||||||||:|..|       ..|.||..:..
  Fly   408 LEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTKWKKQDNV-------TNNEAAEHKSS 465

  Fly   460 G---GATPYLSAWPYAAAAAAQSPHGATPSAIDIYYRQAAAAAAMQK-PSLP--ASYRMYQSSIP 518
            .   |||...:..|.......:|.:..:|:.     ..||..|.::| |..|  .|.....:::.
  Fly   466 NAKPGATGTATTTPSGEPTDKRSSNATSPTV-----GNAATIAEIKKSPKSPNRGSNNNNNNTLN 525

  Fly   519 PGMSLPGMPAPPPPGAAPMLSGYYAAAAAAAASAGAQQQQQQPPAASRSPATSQSANSEADCERT 583
            ..::......|.......:.....|.......:|....:..:..::.:.||..:..|:..:
  Fly   526 NNVNNSEGKVPAKQSTTKIKKQLNALLEKTVKTANQAHRSAELESSDQKPAVEKRPNNSNE---- 586

  Fly   584 SSSSRQRL--------ITPSPPL---------NPGSPPHRE------------------------ 607
            :....|||        :.|:.||         ...||.|||
  Fly   587 NQLLHQRLHQHAIPLTVEPAAPLEQTEKLDIKREESPQHRELQLSLQRAAIQNGQLTEMDFESKL 651

  Fly   608 ---RIN----------EEEDRERDEERDIERERERERERDEDDEE 639
               :|:          :.|.|.:.|....|.|.:.:.|.:|::||
  Fly   652 AASKISIALAMANKQMQPEKRVKTESSSSEGEGDGDGEEEEEEEE 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	31/55 (56%)
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	31/55 (56%)