Protein Alignment B-H2 and HOXC11

DIOPT Version :10

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_055027.1
• Gene: HOXC11 / 3227
• HGNCID: 5123
• Length: 304
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 70/330 - (21%)
• Similarity: 131/330 - (39%)
• Gaps: 74/330 - (22%)

  Fly   153 REREREHYRERHSPPGN--NPYAHHPMPPHLLAHFPPAHYAVLQQQQQQQQQQQHPHPHHLQLER 215
            |:.....:.||.|...|  .|...:.||          .::.:.....|...:|..:|:..|:
Human    15 RKERGADFGERGSCASNLYLPSCTYYMP----------EFSTVSSFLPQAPSRQISYPYSAQV-- 67

  Fly   216 ERLEALHRHGHGLTGDPAQHLSHLSHLSHQQHHPHLHHP--------MHDE----RSRSPLMLQQ 268
                           .|.:.:|:....|.:.||.:.:..        ||.|    .:.:.::::.
Human    68 ---------------PPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPSTVTEILMKN 117

  Fly   269 LGGNGGNNNNNNNNSSSASNNNNNNNNSASANS------NIISGNSSSSNNNNGSGNGNMLLGGP 327
            .|..||:::.:..:::.|...::.|.||....:      |...|..........||.|. ..|.|
Human   118 EGSYGGHHHPSAPHATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDPPAEPPCSGKGE-AKGEP 181

  Fly   328 GSSISGDQASTIDDSDSDDCGGKDDDGDDSMKNGSSANGDSSSHLSLSLSK-----------KQR 381
            .:..:...||..:       .|.:.:.::...|.||:   .|:|   |::|           :.|
Human   182 EAPPASGLASRAE-------AGAEAEAEEENTNPSSS---GSAH---SVAKEPAKGAAPNAPRTR 233

  Fly   382 KARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELL 446
            |.|..::..|::.||:.|....|::.:.|::|:..|.|:|.|||.|:||||.|.|:.:...|:..
Human   234 KKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYF 298

  Fly   447 AEAGN 451
              :||
Human   299 --SGN 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	22/55 (40%)
HOXC11	NP_055027.1	DUF3528	42..161	CDD:432284	21/145 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..237		17/84 (20%)
		Homeodomain	233..289	CDD:459649	22/55 (40%)