Protein Alignment B-H2 and TLX1

DIOPT Version :9

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: XP_011538046.1
• Gene: TLX1 / 3195
• HGNCID: 5056
• Length: 342
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 81/314 - (25%)
• Similarity: 104/314 - (33%)
• Gaps: 112/314 - (35%)

  Fly   239 LSHLSHQQHHPHLHHPMH--------DERSRSP---------LMLQQ----LG---------GNG 273
            :.||.     ||..||.|        |:...||         ..||.    ||         |.|
Human     1 MEHLG-----PHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG 60

  Fly   274 GNNNNNNNNSSSASNNNNNNNNSASANSNIISGNSSSSNNNNGSGNGNM-LLGGPGSSISGDQAS 337
            |:........:.|............|.    .|.:.|.....||.|.|| |.||||....|
Human    61 GSAAATGAGGAGAYGTGGPGGPGGPAG----GGGACSMGPLTGSYNVNMALAGGPGPGGGG---- 117

  Fly   338 TIDDSDSDDCGGKDDDG----------------DDSMKNG------------------------S 362
                ..|...|.....|                ...:..|                        .
Human   118 ----GSSGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWME 178

  Fly   363 SANGDSSSHLSLSLS-----------------KKQRKARTAFTDHQLQTLEKSFERQKYLSVQDR 410
            |....:....:::||                 .|::|.||:||..|:..|||.|.|||||:..:|
Human   179 SNRRYTKDRFTVALSPFTVTRRIGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAER 243

  Fly   411 MELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGN-------YAAFQR 457
            ..||..|:::|.|||||:|||||||:||||...|...:..|       ..|||:
Human   244 AALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQK 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeobox	384..436	CDD:278475	30/51 (59%)
TLX1	XP_011538046.1	Homeobox	216..269	CDD:278475	30/52 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810