Protein Alignment B-H2 and HMX2

DIOPT Version :10

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_005510.1
• Gene: HMX2 / 3167
• HGNCID: 5018
• Length: 273
• Species: Homo sapiens
• Alignment Length: 217
• Identity: 62/217 - (28%)
• Similarity: 95/217 - (43%)
• Gaps: 52/217 - (23%)

  Fly   316 GSGNGNMLLGGPGSSISGDQASTIDDSDSDDCGGKDDDGDDSMKNGSSANG-----DSSSHLSLS 375
            |||.     .|||..   ::...:..|.||    ..::.:..:..||.:.|     |..:.....
Human    94 GSGG-----SGPGGL---ERTPFLSPSHSD----FKEEKERLLPAGSPSPGSERPRDGGAERQAG 146

  Fly   376 LSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTA 440
            .:||  |.||.|:..|:..||.:|:.::|||..:|..||:.|:|::.|||||:||||.|||||.:
Human   147 AAKK--KTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLS 209

  Fly   441 VGLELLAEAGNYAAFQRLYGGATPYLSAWPYAAAAAAQSPHGATPSAIDIYYRQAAAAAAMQKPS 505
            ..|    ||.|                    .|.|:||     |..::.:.:|.::........|
Human   210 AEL----EAAN--------------------MAHASAQ-----TLVSMPLVFRDSSLLRVPVPRS 245

  Fly   506 LPASYRMYQSSIPPGMSLPGMP 527
            |.....:|.    ||.:|..:|
Human   246 LAFPAPLYY----PGSNLSALP 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	27/55 (49%)
HMX2	NP_005510.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..152		15/71 (21%)
		Homeodomain	150..206	CDD:459649	28/57 (49%)