Protein Alignment B-H2 and vnd

DIOPT Version :10

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Alignment Length: 674
• Identity: 171/674 - (25%)
• Similarity: 234/674 - (34%)
• Gaps: 242/674 - (35%)

  Fly     4 MPPEMSATTAA--------------PVGSAPSATAHHPAAVGGGMPRPASPAVGSNTTTATATTA 54
            |.|..:|..||              |...|....|.:|||:...:|         ....|...::
  Fly   140 MLPSSAAVAAAAAAPFLPWSPILLPPWNHALLPAAFYPAALRNALP---------GLFDAKVPSS 195

  Fly    55 TRSRFMITDI--LAGAAAASAAAAAAAAA---------LAAASSGGGRG----------SPTDSE 98
            .||.|.|:||  |.|:...:|||||||||         .|:.|:.|.||          |||.:
  Fly   196 QRSGFHISDILNLEGSELKNAAAAAAAAAHHGSDLSHHSASESTSGHRGQGSHTSPSALSPTPA- 259

  Fly    99 REQSLVAQHHH-------------HHQQQQQHHHHQQQQQQQQHQQAALQQYIVQQQQLLRFERE 150
               .:.|..||             ||...:  ||......||||
  Fly   260 ---GVSADEHHNGSGTGGGAGEADHHSTTE--HHAPPSHPQQQH--------------------- 298

  Fly   151 REREREREHYRERHSPPGNNPYAHHPMPPHLLAHFPPAHYAVLQQQQQQQQQQQHPHPH----HL 211
                   .|:::.|.|....|..||   ...:|..|.||:       |..:.|.|.|.:    ||
  Fly   299 -------PHHQQHHHPHLLLPQQHH---QQAVAPLPLAHH-------QSGEAQSHAHANAAAAHL 346

  Fly   212 QLER-----------ERLEALHRHGHGLTGDPAQHLSHLSH--LSH----------------QQH 247
            ....           :.|..|.::..|..||......|::.  |.|                |..
  Fly   347 LASHNAAAAAAVAAGQYLPNLPKNFPGSFGDEMSSYHHMAQTMLQHSGRSAWIKENELYGTQQPA 411

  Fly   248 HPHLHHPMHDERS---------RSPLM---------------------LQQLGGNGGNNNNNNNN 282
            .|....|:..|.|         .||.:                     |..|.|:.||.:.....
  Fly   412 SPDSTSPVTSEVSYTYIGSNCQTSPALSGDYKSYSRSADSDALSVGDALHTLHGSSGNGSAGGAP 476

  Fly   283 SSSASNNNNNNNNSASANSNIISGNSSSSNNNNGSGNGNMLLGGPGSSISGDQ-ASTIDD-SDSD 345
            ::.|.:|||||    :.|:|   .:|..:...||:|:|:      ..|::.|. ...||| .|:|
  Fly   477 TAHALHNNNNN----TTNNN---NHSLKAEGINGAGSGH------DDSLNEDGIEEDIDDVDDAD 528

  Fly   346 DCGGKDDDGDDSMKNGSSANGDSSSHLSLSLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDR 410
            ..||.|.:|.|.:.|                  |:||.|..||..|...||:.|.:|:|||..:|
  Fly   529 GSGGGDANGSDGLPN------------------KKRKRRVLFTKAQTYELERRFRQQRYLSAPER 575

  Fly   411 MELANKLELSDCQVKTWYQNRRTKWKR-QTAVGLELLAEAGNYAAFQRLYGGATPYLSAWPYAAA 474
            ..||:.:.|:..|||.|:||.|.|.|| |...|.|  ...|      .|:|.||
  Fly   576 EHLASLIRLTPTQVKIWFQNHRYKTKRAQNEKGYE--GHPG------LLHGHAT----------- 621

  Fly   475 AAAQSPH--GATPS----AIDIYYRQAAAAAAMQKPSLPASYRMYQSSIPPGMSLPGMPAPPPPG 533
                .||  .|.||    |:.:..|..       ||.|..|.::....:    |:....|.....
  Fly   622 ----HPHHPSALPSPRRVAVPVLVRNG-------KPCLGDSSKLGADCV----SVSSATATAMQN 671

  Fly   534 AAP----MLSGYYAAAAAAAASAG 553
            ||.    .|:|..|...||||:||
  Fly   672 AAAHHLVALNGAAAYQHAAAAAAG 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	25/55 (45%)
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	25/55 (45%)