Protein Alignment B-H2 and nkx2.5

DIOPT Version :10

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_571496.2
• Gene: nkx2.5 / 30696
• ZFINID: ZDB-GENE-980526-321
• Length: 314
• Species: Danio rerio
• Alignment Length: 270
• Identity: 69/270 - (25%)
• Similarity: 100/270 - (37%)
• Gaps: 64/270 - (23%)

  Fly   306 GNSSSSNNNNGSG--NGNMLLGGPGSSISGDQASTIDDSDSDDCGGKDDDGDDSMKNGSSANGDS 368
            ||..:|.|.:.||  ..|.|..........|  .|.:|.:..|.|...:|..:.:|...:..
Zfish    76 GNKINSINFSASGFYAKNFLEMDYVKDAKTD--DTFEDKEKKDIGCCQEDPGEDLKLDDAER--- 135

  Fly   369 SSHLSLSLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRT 433
                  ...:|:||.|..|:..|:..||:.|::|||||..:|..|||.|:|:..|||.|:||||.
Zfish   136 ------PKQRKRRKPRVLFSQAQVYELERRFKQQKYLSAPERDHLANVLKLTSTQVKIWFQNRRY 194

  Fly   434 KWKRQTA-VGLELLAEA------------------GNYAAFQRLYGGATPYLSAWPYAAAAAAQS 479
            |.|||.. ..||::..|                  |:.:.:...|.....:.:...|.|.:...|
Zfish   195 KCKRQRQDQTLEMVGIAPPRRISVPVLVRDGKPCLGDTSTYNTSYNVGINHFTYNTYPAFSNFPS 259

  Fly   480 PHGATPSAIDIYYRQAAAAAAMQKPSLPASYRMYQSSIPPGMS-----------LPGMPAPPPPG 533
            |..:..|                     .:|....|||.|..|           |..:.|.....
Zfish   260 PGNSNYS---------------------CNYPSSMSSIQPSQSNSNYMNFGVGDLNNVQASFQSS 303

  Fly   534 AAPMLSGYYA 543
            :.|.|.|..|
Zfish   304 SVPSLHGIRA 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	28/55 (51%)
nkx2.5	NP_571496.2	Homeodomain	142..198	CDD:459649	28/55 (51%)