Protein Alignment B-H2 and Tlx1

DIOPT Version :10

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: XP_006526978.1
• Gene: Tlx1 / 21908
• MGIID: 98769
• Length: 345
• Species: Mus musculus
• Alignment Length: 322
• Identity: 81/322 - (25%)
• Similarity: 107/322 - (33%)
• Gaps: 125/322 - (38%)

  Fly   239 LSHLSHQQHHPHLHHPMH--------DERSRSP---------LMLQQ----LG---------GNG 273
            :.||.     ||..||.|        |:...||         ..||.    ||         |.|
Mouse     1 MEHLG-----PHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGDYGLGCLVGGAYTYGGG 60

  Fly   274 GNNNNNNNNSSSASNNNNNNNNSASANSNIISGNSSSSNNNNGSGNGNM-LLGGPGSSISGDQAS 337
            |:........:.|............|..   .|.:.|.....||.|.|| |.||||....|
Mouse    61 GSAAGAGAGGTGAYGAGGPGGPGGPAGG---GGGACSMGPLPGSYNVNMALAGGPGPGGGG---- 118

  Fly   338 TIDDSDSDDCGGKDDDGDDSMK-------------NGSSANGD---------------------- 367
                      ||....|..::.             .|:.|:..
Mouse   119 ----------GGGGAGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAVPGVNNLT 173

  Fly   368 -------------SSSHLSLSLS-----------------KKQRKARTAFTDHQLQTLEKSFERQ 402
                         :....:::||                 .|::|.||:||..|:..|||.|.||
Mouse   174 GLTFPWMESNRRYTKDRFTVALSPFTVTRRIGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQ 238

  Fly   403 KYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGN-------YAAFQR 457
            |||:..:|..||..|:::|.|||||:|||||||:||||...|...:..|       ..|||:
Mouse   239 KYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQK 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	32/55 (58%)
Tlx1	XP_006526978.1	Homeodomain	217..273	CDD:459649	32/55 (58%)