Protein Alignment B-H2 and EVX1

DIOPT Version :10

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_001980.1
• Gene: EVX1 / 2128
• HGNCID: 3506
• Length: 407
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 91/320 - (28%)
• Similarity: 115/320 - (35%)
• Gaps: 115/320 - (35%)

  Fly   326 GPG------SSISGDQASTIDDSDSD-----------DCG------------------GKDDDGD 355
            |||      .|:||....:..|::||           ||.                  |..:.|.
Human    93 GPGPPAPSVDSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKGSGSEALVGSPNGGS 157

  Fly   356 DSMK-NGSSANGDSSSHLSLSLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLEL 419
            ::.| ||.|..|.|...|:.|.|.:.|:.|||||..|:..|||.|.|:.|:|...|.|||..|.|
Human   158 ETPKSNGGSGGGGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNL 222

  Fly   420 SDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGATPYLSAWPYAAAAAAQSPHGAT 484
            .:..:|.|:||||.|.||                  |||       ...|          ||.|.
Human   223 PETTIKVWFQNRRMKDKR------------------QRL-------AMTW----------PHPAD 252

  Fly   485 PSAIDIYYRQAAAAAAMQKPSLPASYRMYQSSIPPGMSLPGMPAPPPPGAAPMLSGYYAAAAAAA 549
            |:........||||..:..|        :.|.:|       :|...|.|          ..||:|
Human   253 PAFYTYMMSHAAAAGGLPYP--------FPSHLP-------LPYYSPVG----------LGAASA 292

  Fly   550 ASAGAQQQQQQPPAASRSPATSQSANSEADCERTSSS--SRQRLITP--SPPLNPGSPPH 605
            |||.|     .|.:.|..|         .|..|..|.  .|..|:..  .|||.|| |.|
Human   293 ASAAA-----SPFSGSLRP---------LDTFRVLSQPYPRPELLCAFRHPPLYPG-PAH 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	27/55 (49%)
EVX1	NP_001980.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..120		9/26 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..179		9/41 (22%)
		Homeodomain	184..240	CDD:459649	27/55 (49%)