Protein Alignment B-H2 and EMX1

DIOPT Version :10

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_004088.2
• Gene: EMX1 / 2016
• HGNCID: 3340
• Length: 290
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 63/244 - (25%)
• Similarity: 101/244 - (41%)
• Gaps: 58/244 - (23%)

  Fly   270 GGNGGNNNNNNNNSSSASN-----NNNNNNNSASANSNIISGNSSSSNNNNGSGNGNMLLGGP-- 327
            ||.||....::..:::||.     ...|..:.::|.:..:||..:::    .:|.|..|.|||
Human    57 GGTGGGGAGSHLLAAAASEEPLRPTALNYPHPSAAEAAFVSGFPAAA----AAGAGRSLYGGPEL 117

  Fly   328 -------------------GSSISGDQASTIDDSDSDDCG-----------GKDDDGDDSMKNGS 362
                               |:|......|.......|...           |......|..::|.
Human   118 VFPEAMNHPALTVHPAHQLGASPLQPPHSFFGAQHRDPLHFYPWVLRNRFFGHRFQASDVPQDGL 182

  Fly   363 SANGDSSSHLSLSLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTW 427
            ..:|        ..::|.::.||||:..||..||::||:..|:...:|.:||..|.||:.|||.|
Human   183 LLHG--------PFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVW 239

  Fly   428 YQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGATPYLSAWPYAAAAA 476
            :||||||:|||.      |.|.|..:. |:..|  :.:::.|..|...|
Human   240 FQNRRTKYKRQK------LEEEGPESE-QKKKG--SHHINRWRIATKQA 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	27/55 (49%)
EMX1	NP_004088.2	Homeodomain	193..249	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..290		10/40 (25%)