Protein Alignment B-H2 and Nkx3-1

DIOPT Version :10

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_035051.1
• Gene: Nkx3-1 / 18095
• MGIID: 97352
• Length: 237
• Species: Mus musculus
• Alignment Length: 343
• Identity: 79/343 - (23%)
• Similarity: 114/343 - (33%)
• Gaps: 136/343 - (39%)

  Fly   144 LLRFEREREREREREHYRERHSPPGNNPYAHHPMPPHLLAHFPPAHYAVLQQQQQQQQQQQHPHP 208
            :||....||         .|....|.:|:|..|.....|..|      ::|
Mouse     1 MLRVAEPRE---------PRVEAGGRSPWAAPPTQSKRLTSF------LIQ-------------- 36

  Fly   209 HHLQLERERLEALHRHGHGLTGDPAQHLSHLSHLSHQQHHPHLHHPMHDERSRSPLMLQQLGGNG 273
               .:.|:|.|   ||| |.:|:|             ||.|       |.|..|.....:.||.|
Mouse    37 ---DILRDRAE---RHG-GHSGNP-------------QHSP-------DPRRDSAPEPDKAGGRG 74

  Fly   274 GNNNNNNNNSSSASNNNNNNNNSASANSNIISGNSSSSNNNNGSGNGNMLLGGPGSSISGDQAST 338
                                                             :......||....|.|
Mouse    75 -------------------------------------------------VAPEDPPSIRHSPAET 90

  Fly   339 IDDSDSD--------DCGGKDDDGDDSMKNGSSANGDSSSHLSLSLSKKQRKARTAFTDHQLQTL 395
            ..:.:||        ||              ....||.:|...:: .:.|:::|.||:..|:..|
Mouse    91 PTEPESDAHFETYLLDC--------------EHNPGDLASAPQVT-KQPQKRSRAAFSHTQVIEL 140

  Fly   396 EKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKR-QTAVGLELLAEAGNYAAFQRLY 459
            |:.|..|||||..:|..||..|:|::.|||.|:||||.|.|| |.:..|.:| |..:..:...|.
Mouse   141 ERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSEDLGVL-EKNSPLSLPALK 204

  Fly   460 GGATPYLS------AWPY 471
            ..:.|..|      ::||
Mouse   205 DDSLPSTSLVSVYTSYPY 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	26/55 (47%)
Nkx3-1	NP_035051.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..96		34/199 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	108..130		4/22 (18%)
		Homeodomain	126..182	CDD:459649	26/55 (47%)