Protein Alignment B-H2 and DLX3

DIOPT Version :10

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_005211.1
• Gene: DLX3 / 1747
• HGNCID: 2916
• Length: 287
• Species: Homo sapiens
• Alignment Length: 233
• Identity: 65/233 - (27%)
• Similarity: 92/233 - (39%)
• Gaps: 82/233 - (35%)

  Fly   378 KKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVG 442
            ||.||.||.::.:||..|::.|::.:||::.:|.|||.:|.|:..|||.|:||||:|
Human   127 KKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSK-------- 183

  Fly   443 LELLAEAGNYAAFQRLY-GGATPYLSAWPYAAAAAAQSPHGATPSAIDIYYRQAAAAAAMQKPSL 506
                        |::|| .|..|           ...||:.:.             :.|...|..
Human   184 ------------FKKLYKNGEVP-----------LEHSPNNSD-------------SMACNSPPS 212

  Fly   507 PASYRMYQSSIP-PGMSLPGMPAPPPPGAAPML------SGYYAAAAAAAASAGAQQQQQQPPAA 564
            ||.:.....|.| |..|  .:|.|.|..|:|..      |.|:      |.:......|||||
Human   213 PALWDTSSHSTPAPARS--QLPPPLPYSASPSYLDDPTNSWYH------AQNLSGPHLQQQPP-- 267

  Fly   565 SRSPATSQSANSEADCERTSSSSRQRLITPSPPLNPGS 602
              .|||...|                  :|.||.|||:
Human   268 --QPATLHHA------------------SPGPPPNPGA 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	25/55 (45%)
DLX3	NP_005211.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..39
		DLL_N	27..107	CDD:463567
		COG5576	<109..232	CDD:227863	42/150 (28%)
		homeobox	129..188		26/78 (33%)
		Homeodomain	130..186	CDD:459649	26/75 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		33/134 (25%)