Protein Alignment B-H2 and Hoxb5

DIOPT Version :10

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_032294.2
• Gene: Hoxb5 / 15413
• MGIID: 96186
• Length: 269
• Species: Mus musculus
• Alignment Length: 238
• Identity: 66/238 - (27%)
• Similarity: 102/238 - (42%)
• Gaps: 46/238 - (19%)

  Fly   261 RSPLMLQQLGGNGGNNNNNNN---NSSSASNNN------NNNNNSASANS----NIISGNSSSSN 312
            |.|..:..  |:.|.|.|..:   |.||||:::      ::....|||..    ...|..|.||.
Mouse    35 RDPAAMHT--GSYGYNYNGMDLSVNRSSASSSHFGAVGESSRAFPASAQEPRFRQATSSCSLSSP 97

  Fly   313 NNNGSGNGNMLLGGPGSSISGDQASTIDDS------DSDDCGGKDDDGDDSMKNGSSANGDSSS- 370
            .:....||:.....|.:|...|||:....|      |......:.::....:.:.|.|......
Mouse    98 ESLPCTNGDSHGAKPSASSPSDQATPASSSANFTEIDEASASSEPEEAASQLSSPSLARAQPEPM 162

  Fly   371 ---------------------HLSLSLSKKQ-RKARTAFTDHQLQTLEKSFERQKYLSVQDRMEL 413
                                 |:|..::... ::||||:|.:|...|||.|...:||:.:.|:|:
Mouse   163 ATSTAAPEGQTPQIFPWMRKLHISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEI 227

  Fly   414 ANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQ 456
            |:.|.||:.|:|.|:||||.|||:...:....||.||  :|||
Mouse   228 AHALCLSERQIKIWFQNRRMKWKKDNKLKSMSLATAG--SAFQ 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	27/55 (49%)
Hoxb5	NP_032294.2	PRK07003	<67..>171	CDD:235906	18/103 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..173		18/97 (19%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeodomain	195..251	CDD:459649	27/55 (49%)