Protein Alignment B-H2 and Dbx1

DIOPT Version :10

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_001005232.1
• Gene: Dbx1 / 13172
• MGIID: 94867
• Length: 335
• Species: Mus musculus
• Alignment Length: 250
• Identity: 65/250 - (26%)
• Similarity: 86/250 - (34%)
• Gaps: 93/250 - (37%)

  Fly   374 LSLSKKQRKA---RTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKW 435
            |:...|.|:.   |..|:|.|.:.|||:|::|||:|..||.:||:||.|.|.|||.|:||||.||
Mouse   172 LAARGKPRRGMLRRAVFSDVQRKALEKTFQKQKYISKPDRKKLASKLGLKDSQVKIWFQNRRMKW 236

  Fly   436 KRQTAVGLELLAEAGNYAAFQRLYGGATPYLSAWPYAAAAAAQSPHGATPSAIDIYYRQAAAAAA 500
            :....  .|||:..|
Mouse   237 RNSKE--RELLSSGG-------------------------------------------------- 249

  Fly   501 MQKPSLPASYRMYQSSIPPGMSLPGMPAPPPPGAAPMLSGYYAAAAAAAASAGAQQQQQQPPAAS 565
            .::.:||.....:......|...||......|||.   ..|:|.|.......|..      ||
Mouse   250 CREQTLPTKLNPHPDLSDVGQKGPGDEEEDNPGAR---LAYHAPADPRHLLEGPL------PA-- 303

  Fly   566 RSPATSQSANSEADCERTSSSSRQRLITPSPPLNPGSPPHRERINEEEDRERDEE 620
             |||.|.|                          ||.|......:|:|:.|.|||
Mouse   304 -SPAHSSS--------------------------PGKPSDFSDSDEDEEGEEDEE 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	31/58 (53%)
Dbx1	NP_001005232.1	PRK12323	<49..182	CDD:481241	3/9 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	58..102
		Homeodomain	184..238	CDD:459649	30/53 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..335		31/181 (17%)