Protein Alignment B-H2 and LBX1

DIOPT Version :10

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_006553.2
• Gene: LBX1 / 10660
• HGNCID: 16960
• Length: 281
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 76/253 - (30%)
• Similarity: 100/253 - (39%)
• Gaps: 101/253 - (39%)

  Fly   378 KKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVG 442
            ||:||:|||||:||:..|||.|..|||||..||.::|.:|.|::.||.||:||||.|.||...
Human   123 KKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLE-- 185

  Fly   443 LELLAEAGNYAAFQRLYGGATPYLSAWPYAAAAAAQSPHGATPSAIDIYYRQAAAAAAMQKPSLP 507
             |:.|:                       ..:|....|.|    .:||     .|.|.:::.|
Human   186 -EMKAD-----------------------VESAKKLGPSG----QMDI-----VALAELEQNS-- 215

  Fly   508 ASYRMYQSSIPPG------MSLPGMPAPPPPGAAPMLSGYYAAAAAAAASAGAQQQQQQPPAASR 566
                  :::...|      .|.||.|..||             .|..|..|||.|..   ||
Human   216 ------EATAGGGGGCGRAKSRPGSPVLPP-------------GAPKAPGAGALQLS---PA--- 255

  Fly   567 SPATSQSANSEADCERTSSSSRQRLITPSPPLNPGSPPHRERINEEEDRERDEERDIE 624
            ||.|.|.|:|: ||                               .|| |.|||.|::
Human   256 SPLTDQPASSQ-DC-------------------------------SED-EEDEEIDVD 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	32/55 (58%)
LBX1	NP_006553.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..35
		Homeodomain	126..182	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..281		31/127 (24%)