Protein Alignment B-H2 and Barhl2

DIOPT Version :9

• Sequence 1: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_001005477.1
• Gene: Barhl2 / 104382
• MGIID: 1859314
• Length: 384
• Species: Mus musculus
• Alignment Length: 528
• Identity: 149/528 - (28%)
• Similarity: 187/528 - (35%)
• Gaps: 203/528 - (38%)

  Fly    54 ATRSRFMITDILAGAAAAS-------------------AAAAAAAAALAAASSGGGRGSP---TD 96
            |:.|.|.|..||:||.:.|                   .:.|..:......:.|....||   |.
Mouse     7 ASGSSFGIDTILSGAGSGSPGMMNGDFRSLGEARTTDFRSQATPSPCSEIDTVGTAPSSPISVTL 71

  Fly    97 SEREQSLVA---QHHHHHQQQQQHHHHQQQQQQQQHQQAALQQYIVQQQQLLRFERERERERERE 158
            ...|..||.   ||||       |.||.||
Mouse    72 EPPEPHLVTDGPQHHH-------HLHHSQQ----------------------------------- 94

  Fly   159 HYRERHSPPGNNPYAHHPMPPHLLAHFPPAHYAVLQQQQQQQQQQQHPHPHHLQLERERLEALHR 223
                             |.||..:    ||     |..|...|||..|.|.....:.....|..|
Mouse    95 -----------------PPPPSAV----PA-----QSLQPSPQQQPPPQPQSAAQQLGSAAAAPR 133

  Fly   224 HG------HGLTGDPAQHLSHLSHLSHQQHHPHLHHPMHDERSRSPLMLQQLGGNGGNNNNNNNN 282
            ..      ..:.|| ::.|:..:..|.....|| |.|..:..:.......:|....|....:..
Mouse   134 TSTSSFLIKDILGD-SKPLAACAPYSTSVSSPH-HTPKQESNAAHESFRPKLEQEDGKTKLDKR- 195

  Fly   283 SSSASNNNNNNNNSASANSNIISGNSSSSNNNNGSGNGNMLLGGPGSSISGDQASTIDDSDSD-D 346
                                                                     :|..|| .
Mouse   196 ---------------------------------------------------------EDPQSDIK 203

  Fly   347 CGGKDDDGDDSMKNGSSANGDSSSHLSLSL-SKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDR 410
            |.|..::||..:         :||..|..: :||.|||||||:||||..||:|||||||||||||
Mouse   204 CHGTKEEGDREI---------TSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDR 259

  Fly   411 MELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGATPYL--------- 466
            |:||..|.|:|.||||||||||||||||||||||||||||||:|.||::  .:||.
Mouse   260 MDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF--PSPYFYHPSLLGSM 322

  Fly   467 -SAWPYAAAAAAQSPHGATPSAIDIYYRQAAAAAAMQKPSLPASYRMYQSSIPPG---------M 521
             |....|||||..|....||         .|....:|:|.:|   |:....:.||         .
Mouse   323 DSTTAAAAAAAMYSSMYRTP---------PAPHPQLQRPLVP---RVLIHGLGPGGQPALNPLSN 375

  Fly   522 SLPGMPAP 529
            .:||.|.|
Mouse   376 PIPGTPHP 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H2	NP_523386.1	Homeobox	384..436	CDD:278475	41/51 (80%)
Barhl2	NP_001005477.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..134		39/194 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	154..235		23/148 (16%)
		Homeobox	233..285	CDD:278475	41/51 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..384		6/20 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833021
Domainoid	1	1.000	103	1.000	Domainoid score	I6762
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002353
OrthoInspector	1	1.000	-	-		mtm8702
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24330
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10747
SonicParanoid	1	1.000	-	-		X1387
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.920