Protein Alignment Fim and FIM5

DIOPT Version :9

• Sequence 1: NP_728074.1
• Gene: Fim / 32721
• FlyBaseID: FBgn0024238
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_198420.1
• Gene: FIM5 / 833544
• AraportID: AT5G35700
• Length: 687
• Species: Arabidopsis thaliana
• Alignment Length: 635
• Identity: 234/635 - (36%)
• Similarity: 367/635 - (57%)
• Gaps: 42/635 - (6%)

  Fly    35 IDLHELKDALNQVGFKLAGYQVREMIDEYKGKQLTAFQGKLNLEEFEALCLDLKSKDVAS----- 94
            ::|..||........:|..:.|.::...:  ::|.||.|.::.:|.::: || ||...|.
plant    21 VELRTLKSKFVSNKTQLGRFTVGDLPPVF--EKLKAFNGTIDEDEIKSV-LD-KSYPNADDEVDF 81

  Fly    95 -----TFKTVVSKKENLETLGGMSSISS---EGTT---HSVRLEEQLAFSDWINSNLGHDKDLQH 148
                 .|.:|.::  .:|..||....||   ..||   |::...|:.::...:|:.|..|..|:.
plant    82 EFFLRAFLSVQAR--GVEKSGGSKGASSFLKTSTTTVHHAINESEKASYVSHVNNYLRDDPFLKS 144

  Fly   149 LLPIDSEGKRLYLSIKDGILLCKIINHSCPDTIDERAIN-KKNLTVYREFENLTLALVSSQAIGC 212
            .||||......:..:|||:||||:||.:.|.|||||||| ||.|..:...|||||.|.|::||||
plant   145 YLPIDPATNAFFDLVKDGVLLCKLINVAVPGTIDERAINTKKTLNPWERNENLTLGLNSAKAIGC 209

  Fly   213 NIVNIDAHDLAKGKPHLVLGLLWQIIRIGLFSHITLDSCPGLAGLLFDNERLEDLMKMSPEAILL 277
            .:|||...|:|:|:|:|||||:.|||:|.:.:.:.....|.|..|:.|.:..|:||.::||.:||
plant   210 TVVNIGTQDIAEGRPYLVLGLISQIIKIQMLADLNFKKTPSLFQLVDDTQDAEELMGLAPEKVLL 274

  Fly   278 RWVNHHLERAGISRRCTNFQSDIVDSEIYSHLLKQIAGNDADVNLDALRESDLQSRAEIMLQQAA 342
            :|:|.||::||..::.|||.||:.|.|.|::||..:|...:  ...||...|...||:.:|:||.
plant   275 KWMNFHLKKAGYEKQVTNFSSDLKDGEAYAYLLNALAPEHS--THVALETKDPTERAKKVLEQAE 337

  Fly   343 KLNCRSFLTPQDVVNGVYKLNLAFVANLFNNHPGL----DKPEQIEGL-ESIEETREEKTYRNWM 402
            ||:|:.:|:|:|:|:|...|||||||.:|.:..||    .|....|.: :.:|.:|||:.:|.|:
plant   338 KLDCKRYLSPKDIVDGSANLNLAFVAQIFQHRNGLTVDDSKTSFAEMMTDDVETSREERCFRLWI 402

  Fly   403 NSMGVAPHVNWLYSDLADGLVIFQLFDVIKPGIVNWSRVHKRFSPLRKFMEKLENCNYAVDLGKQ 467
            ||:|.|.:||.::.||.:|.|:.::.|.:.||.|||...:|  .|::...:|:||||..:.:||:
plant   403 NSLGTATYVNNVFEDLRNGWVLLEVLDKVSPGSVNWKHANK--PPIKMPFKKVENCNEVIKIGKE 465

  Fly   468 LKFSLVGIAGQDLNDGNATLTLALIWQLMRAYTLSILSRLA--NTGNPIIEKEIVQWVNNRLSEA 530
            |:||||.:||.|:..||..|.||.:|||||...|.:|..|.  :.|..|.:.:|:.|.|.::...
plant   466 LRFSLVNVAGNDIVQGNKKLLLAFLWQLMRYTMLQLLRNLRSHSQGKEITDADILNWANRKVKRG 530

  Fly   531 GKQSQLRNFNDPAIADGKIVIDLIDAIKEGSINYELVRTSGTQEDNLANAKYAISMARKIGARVY 595
            |:.||..:|.|..::.|...::|:.|::...:|:.||....|:||...||.|.||:|||:|..::
plant   531 GRTSQADSFRDKNLSSGMFFLELLSAVEPRVVNWSLVTNGETEEDKKLNATYIISVARKLGCSIF 595

  Fly   596 ALPEDITEVKPKMVMTVFACMM--------ALDYVPNMDSVDQNNHNSSA 637
            .|||||.||..||::.:.|.:|        ..:...:.|:.|..:.||.|
plant   596 LLPEDIIEVNQKMMLILAASIMYWSLQQQSDTESTVSEDATDDGDANSVA 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fim	NP_728074.1	EF-hand_7	27..84	CDD:290234	10/48 (21%)
		EFh	27..80	CDD:298682	9/44 (20%)
		CH	127..237	CDD:278723	53/110 (48%)
		CH	271..370	CDD:278723	44/98 (45%)
		CH	396..497	CDD:214479	43/100 (43%)
		CH	517..619	CDD:214479	37/109 (34%)
FIM5	NP_198420.1	CH_AtFIM_like_rpt1	123..238	CDD:409142	56/114 (49%)
		CH_AtFIM_like_rpt2	259..367	CDD:409145	47/109 (43%)
		CH_AtFIM_like_rpt3	390..503	CDD:409148	50/114 (44%)
		CH_AtFIM_like_rpt4	513..621	CDD:409151	38/107 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	112	1.000	Domainoid score	I2057
eggNOG	1	0.900	-	-		E2759_KOG0046
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H80174
Inparanoid	1	1.050	405	1.000	Inparanoid score	I459
OMA	1	1.010	-	-		QHG54335
OrthoDB	1	1.010	-	-		D312506at2759
OrthoFinder	1	1.000	-	-		FOG0000930
OrthoInspector	1	1.000	-	-		otm2525
orthoMCL	1	0.900	-	-		OOG6_101115
Panther	1	1.100	-	-	O	PTHR19961
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X500
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840