Protein Alignment Fim and pls1

DIOPT Version :9

• Sequence 1: NP_728074.1
• Gene: Fim / 32721
• FlyBaseID: FBgn0024238
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_017213221.1
• Gene: pls1 / 334273
• ZFINID: ZDB-GENE-030131-6205
• Length: 665
• Species: Danio rerio
• Alignment Length: 624
• Identity: 316/624 - (50%)
• Similarity: 428/624 - (68%)
• Gaps: 28/624 - (4%)

  Fly    11 QTVQEFKQNLEELIPNLDANKDGFIDLHELKDALNQVGFKLAGYQVREMIDEYKGKQLTAFQGKL 75
            |..:|..::|.|....:|.:..|::...||::...:..|.|.|||:||:::::.... |....|:
Zfish    44 QISREDLEDLREAFNKIDIDNSGYVSDFELQELFREASFHLPGYQIREIVEKFIAGD-TNKDEKI 107

  Fly    76 NLEEFEALCLDLKSKDVASTFKTVVSKKENLETLGGMSSISSEGTTHSVRLEEQLAFSDWINSNL 140
            :.|||.|:..:|:||:|..||:..:|:::.:.:.||.|.||||||.||...||::||.:|:|..|
Zfish   108 SFEEFVAISQELRSKEVRETFRKCISRRDGIRSFGGTSGISSEGTQHSYSDEEKVAFVNWVNKAL 172

  Fly   141 GHDKDLQHLLPIDSEGKRLYLSIKDGILLCKIINHSCPDTIDERAINKKNLTVYREFENLTLALV 205
            .:|.|.:||:|:|.....|:.|:||||||||:||.|.|||||||.|||| .|.:...|||.|||.
Zfish   173 ANDPDCKHLIPMDPGTDSLFKSVKDGILLCKMINLSQPDTIDERVINKK-CTPFTMTENLMLALN 236

  Fly   206 SSQAIGCNIVNIDAHDLAKGKPHLVLGLLWQIIRIGLFSHITLDSCPGLAGLLFDNERLEDLMKM 270
            |:.||||.:|||||.|:..|.||||||||||||:||||:.|.:.....|..||.::|.|:.||.|
Zfish   237 SASAIGCTVVNIDAQDMKAGTPHLVLGLLWQIIKIGLFADIEISRNEALIALLDESEELDHLMSM 301

  Fly   271 SPEAILLRWVNHHLERAGISRRCTNFQSDIVDSEIYSHLLKQIAGND-------ADVNLDALRES 328
            |||.:||||||:||:.|| .::..||..||.||..|.|||.||:...       .|:::..|.|.
Zfish   302 SPEDLLLRWVNYHLKAAG-WKQIRNFSEDIKDSRAYFHLLNQISPKGDLDDQMRIDIDMLGLTER 365

  Fly   329 DLQSRAEIMLQQAAKLNCRSFLTPQDVVNGVYKLNLAFVANLFNNHPGLDKPEQ------IEGLE 387
            |.:.|||:||:|||:|:||.|:||:|||.|.:|||:||||||||.:|.|::|..      |||
Zfish   366 DDEMRAELMLRQAARLDCRQFVTPKDVVAGNHKLNMAFVANLFNMYPALNRPTDNGIDYAIEG-- 428

  Fly   388 SIEETREEKTYRNWMNSMGVAPHVNWLYSDLADGLVIFQLFDVIK-PGIVNWSRVHKRFSP-LRK 450
               ||||::|:||||||:||:|:||.|||||.|||:|.||::.|: |  |:|.||:|...| |..
Zfish   429 ---ETREDRTFRNWMNSLGVSPYVNHLYSDLHDGLIILQLYERIQIP--VDWPRVNKPPYPVLGS 488

  Fly   451 FMEKLENCNYAVDLG-KQLKFSLVGIAGQDLNDGNATLTLALIWQLMRAYTLSILSRLANTGNPI 514
            .|:|||||||||.|| |:.|||||||.|:::|:|:...||||:|||||.|||.:||.|.: |..:
Zfish   489 NMKKLENCNYAVALGKKEAKFSLVGIGGENINEGSPMHTLALVWQLMRRYTLKVLSDLGD-GEKV 552

  Fly   515 IEKEIVQWVNNRLSEAGKQSQLRNFNDPAIADGKIVIDLIDAIKEGSINYELVRTSG-TQEDNLA 578
            .::.|:.|||:.|.:..|.|.:.:|.|.:|:....||||||.|...:|.||:|::.. |.||.|.
Zfish   553 SDQIIINWVNSTLKQGDKNSSISSFKDKSISTSLPVIDLIDTIVPKAIKYEMVKSGDMTAEDKLN 617

  Fly   579 NAKYAISMARKIGARVYALPEDITEVKPKMVMTVFACMM 617
            |||||||:|||||.:|||||:|:.|||||||||||||:|
Zfish   618 NAKYAISVARKIGVKVYALPDDLVEVKPKMVMTVFACLM 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fim	NP_728074.1	EF-hand_7	27..84	CDD:290234	17/56 (30%)
		EFh	27..80	CDD:298682	14/52 (27%)
		CH	127..237	CDD:278723	65/109 (60%)
		CH	271..370	CDD:278723	54/105 (51%)
		CH	396..497	CDD:214479	62/103 (60%)
		CH	517..619	CDD:214479	57/102 (56%)
pls1	XP_017213221.1	SAC6	35..656	CDD:227401	315/622 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587941
Domainoid	1	1.000	140	1.000	Domainoid score	I4702
eggNOG	1	0.900	-	-		E2759_KOG0046
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	599	1.000	Inparanoid score	I923
OMA	1	1.010	-	-		QHG54335
OrthoDB	1	1.010	-	-		D138895at33208
OrthoFinder	1	1.000	-	-		FOG0000930
OrthoInspector	1	1.000	-	-		otm25149
orthoMCL	1	0.900	-	-		OOG6_101115
Panther	1	1.100	-	-	LDO	PTHR19961
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X500
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.770