DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fim and Y73B3B.1

DIOPT Version :10

Sequence 1:NP_728074.1 Gene:Fim / 32721 FlyBaseID:FBgn0024238 Length:641 Species:Drosophila melanogaster
Sequence 2:NP_508051.1 Gene:Y73B3B.1 / 190640 WormBaseID:WBGene00022223 Length:376 Species:Caenorhabditis elegans


Alignment Length:363 Identity:123/363 - (33%)
Similarity:197/363 - (54%) Gaps:68/363 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   325 LRESDLQSRAEIMLQQAAKLNCRSFLTPQDVVNGVYKLNLAFVANLFNNHPGLDKPEQIEGLESI 389
            |.|..::.|..:|...||::: ..|.|....:..| :|:.......|.::.|..|   ::|.::|
 Worm     4 LEEYSIEERVRVMFGSAAEVS-NDFRTQIRTIGDV-ELDEKHRICKFTSYDGKLK---LQGDQNI 63

  Fly   390 EETREEKTYRNWMNSMGVAPHVNWL-------------------YSDL-----ADGLVIFQLFDV 430
             ..|.:|.:...:....:...:|:|                   :|:|     .||:...:.::.
 Worm    64 -SARSKKQWPIRVTLAELTGFMNYLVEKTKDTIEPVVAAKLFREFSELEGEGRTDGVYYKRFYNQ 127

  Fly   431 IKPG---IVNWS-----RVHKRFSP--LRKFMEKLENC-NYAVDLGKQL--------KFSLVG-- 474
            :.|.   :|::|     ||...|:.  ...|:.::... :..:|.||::        |.:|.|  
 Worm   128 LAPNMAKLVDYSIEERLRVMFGFAAEVFDDFLAQIRTLGDVELDEGKRISKFTSTDGKLNLEGDH 192

  Fly   475 ----------------IAGQDLNDGNATLTLALIWQLMRAYTLSILSRLANTGNPI-IEKEIVQW 522
                            ..|:.:.|||..|||||:||||||||||:|::...:|:.: .:|:||.|
 Worm   193 SHAARMKRRCAEYRNAYRGRHIYDGNQILTLALVWQLMRAYTLSVLAQYTQSGDSLPTDKDIVAW 257

  Fly   523 VNNRLSEAGKQSQLRNFNDPAIADGKIVIDLIDAIKEGSINYELVRTSGTQEDNLANAKYAISMA 587
            ||.:|..:||.:.:|:|.||||:|||:|:||||:||...|::.||::..:.||.::||||||:..
 Worm   258 VNEKLKNSGKSTSIRSFQDPAISDGKVVLDLIDSIKPNVIDHSLVKSGKSNEDKMSNAKYAITCG 322

  Fly   588 RKIGARVYALPEDITEVKPKMVMTVFACMMALDYVPNM 625
            |||||::|||||||.|||||||:|||||:||.||:|:|
 Worm   323 RKIGAKIYALPEDIVEVKPKMVLTVFACLMARDYLPDM 360

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FimNP_728074.1 EFh 27..80 CDD:415501
CH_PLS_rpt1 104..248 CDD:409141
CH_PLS_rpt2 260..372 CDD:409144 10/46 (22%)
CH_PLS_rpt3 389..504 CDD:409147 41/175 (23%)
CH_PLS_rpt4 514..620 CDD:409150 62/106 (58%)
Y73B3B.1NP_508051.1 SPK <1..59 CDD:214732 13/59 (22%)
SPK 79..190 CDD:214732 18/110 (16%)
CH_SF <211..238 CDD:469584 19/26 (73%)
CH_PLS_rpt4 250..355 CDD:409150 62/104 (60%)
Blue background indicates that the domain is not in the aligned region.

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