Protein Alignment CG8915 and DHX38

DIOPT Version :10

• Sequence 1: NP_573208.1
• Gene: CG8915 / 32715
• FlyBaseID: FBgn0030833
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_054722.2
• Gene: DHX38 / 9785
• HGNCID: 17211
• Length: 1227
• Species: Homo sapiens
• Alignment Length: 914
• Identity: 250/914 - (27%)
• Similarity: 410/914 - (44%)
• Gaps: 147/914 - (16%)

  Fly     4 SEEAVKRGRRQGRKKAQPMPEQAVVLVVNGRVTGGPKGTGKQKTRPGKNAKADAG-------DKL 61
            ||:.|:|..:...|:.|.            |::...:...:...|...|....:|       |:.
Human   344 SEDYVRRREQHLHKQKQK------------RISAQRRQINEDNERWETNRMLTSGVVHRLEVDED 396

  Fly    62 KSEDEK-----MLRQLVDDFLQ-----SCEPEKQLPGLTKAQRSHVHRLAQHRGLKTVSKGPEEN 116
            ..||..     |:..||..||.     :.:||..:|  .|...|.:..:|: :|.:||.|..|:.
Human   397 FEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIP--VKDATSDLAIIAR-KGSQTVRKHREQK 458

  Fly   117 RVLFISRPQSDGQQQYILCNTKLDICPPLLDVLGQMA-----------GNVERRLMNSVGDLKCN 170
                 .|.::. .:.:.|..|||.      |::|...           |.|:.|......|....
Human   459 -----ERKKAQ-HKHWELAGTKLG------DIMGVKKEEEPDKAVTEDGKVDYRTEQKFADHMKR 511

  Fly   171 KQQYKDIRLPSNFGLVGQRLIPPPQSNRNRNIQHERRSLPIYKQRESILNVLQRDQVLIIKGATG 235
            |.:     ..|.|.             :.::|..:|:.|||:..::.:|.:::.:.::|:.|.||
Human   512 KSE-----ASSEFA-------------KKKSILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETG 558

  Fly   236 SGKSTQLPQYILEWAAEHRAPVRIVVSQPRRIAAISVSERISKERGEAPGTTVGYNIRMNRQCSS 300
            |||:|||.||:.|.......  .|..:||||:||:||::|:|:|.|...|..|||.||.....|.
Human   559 SGKTTQLTQYLHEDGYTDYG--MIGCTQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSE 621

  Fly   301 NTVLMLTTSGCLLRALAMDKKSFFKNTTHLIIDEAHERDLDTDFLLLATKLELQKNPHLRLVLMS 365
            ||::...|.|.|||...  :::...:.:.:|:||||||.|:||.|....:..:.:...|:|::.|
Human   622 NTLIKYMTDGILLRESL--READLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIVTS 684

  Fly   366 ATMDLEALSNYFGGGTVMDVEGRSFEVSIYHLEDILSKTGYMHPRMEKFLGKPTGKETPSELLAA 430
            ||||.|..:.:||...:..:.||:|.|.|     :.||                   ||.|
Human   685 ATMDAEKFAAFFGNVPIFHIPGRTFPVDI-----LFSK-------------------TPQE---- 721

  Fly   431 YYGGNTIVHPDIDNDLIVSLLELLLRQGDAGAVIVYLPGYSD--MTS--LLARLESSLPREQITI 491
                 ..|...:...|.|.|      .|..|.:::::||..|  :||  ::..||.......:.:
Human   722 -----DYVEAAVKQSLQVHL------SGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAV 775

  Fly   492 ILLHSQVDNSEQRKVFRTYP-GVRLKIILSTNIGQTSITIPDLLYVIDTGLAKMKTYDSTIDASQ 555
            :.::||:.:..|.|:|:..| ||| |.|::|||.:||:|:..:::|||:|..|:|.::..|....
Human   776 LPIYSQLPSDLQAKIFQKAPDGVR-KCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDA 839

  Fly   556 LTLTWISQADAKQRAGRAGRVCHGNCYRLYDNDRMARMNL-YTIPEIMRRTLDEICLLTK-LAAP 618
            |.:..||||:|.||:|||||...|.|:|||.........| .|:|||.|..|..:.||.| |...
Human   840 LQIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQ 904

  Fly   619 DKKIENFLALALDTPPKDAVMQSCSRLKLLGVLDERDEVTPLGHIVAELPLGVQIGKCLVYSIYL 683
            |....:|    :|.||:|.::.|..:|.:||.||....:|..|.::.|.||...:.|.|:.|..:
Human   905 DLLQFHF----MDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDM 965

  Fly   684 RCLDSMIIIAAYHSVRDPFVLNIERGKKSGQQISRVLFAGDGMSDSLAVIKLYEEFTNLKRKDIG 748
            .|...:::|.:..||  |.:....:|::......|..||.. .||.|..:.:|.::.|.....|
Human   966 GCSSEILLIVSMLSV--PAIFYRPKGREEESDQIREKFAVP-ESDHLTYLNVYLQWKNNNYSTI- 1026

  Fly   749 DFCERNFICRNAMEMFVSAASTLRDTVYRIFRFSEASARLASSFNNDTNMIRLALTAGLYPKLAY 813
             :|..:||...||.......:.|:|.:.: .|.|.||.      ..|.:::|..:.|..:.:.|.
Human  1027 -WCNDHFIHAKAMRKVREVRAQLKDIMVQ-QRMSLASC------GTDWDIVRKCICAAYFHQAAK 1083

  Fly   814 MDRENKNQLVAEGDPLVQVSRSSCLRGKKKQKDLASEWILFVEKTRTADQISSLEHTTLVSGLMV 878
            :....:...:..|.| ..:..:|.|.|.....|    :|::.|...|..:.  ::..|.|.|..:
Human  1084 LKGIGEYVNIRTGMP-CHLHPTSSLFGMGYTPD----YIVYHELVMTTKEY--MQCVTAVDGEWL 1141

  Fly   879 ALAG 882
            |..|
Human  1142 AELG 1145

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8915	NP_573208.1	R3H	67..123	CDD:460206	16/65 (25%)
		HrpA	208..>702	CDD:441249	165/500 (33%)
		OB_NTP_bind	799..884	CDD:400182	17/84 (20%)
DHX38	NP_054722.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	60..320
		HrpA	532..>1146	CDD:441249	205/681 (30%)
		DEAH box	652..655		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1155..1227