DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8915 and AT1G58050

DIOPT Version :9

Sequence 1:	NP_001285369.1	Gene:	CG8915 / 32715	FlyBaseID:	FBgn0030833	Length:	976	Species:	Drosophila melanogaster
Sequence 2:	NP_176102.1	Gene:	AT1G58050 / 842172	AraportID:	AT1G58050	Length:	1417	Species:	Arabidopsis thaliana

Alignment Length:	1087	Identity:	315/1087 - (28%)
Similarity:	492/1087 - (45%)	Gaps:	199/1087 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KRGRRQGRKKA---QPMPEQAVVLVVNGRVTGGPKG----TGKQKTRPGKNAKADAGDKLKSEDE 66
            |:|..|...||   |.......:.....:|||..:.    |...:...|......||..:..:
plant   388 KKGEAQKIPKALLHQLCQRSGWIAPKFNKVTGEGRNFSYTTSVMRKSSGFGKSRQAGGLVTIQ-- 450

  Fly    67 KMLRQLVDDF--LQSCEPE----------KQLP---GLTKAQRSHVHRLAQHRGLKTVSKGPEEN 116
              |...|:||  :|..:..          ..||   .:|:...|.|....|...|...|: .|:.
plant   451 --LPHQVEDFESIQDAQNRVAAFALHKLFSDLPVHFAITEPYASLVLIWKQEESLGITSR-EEQR 512

  Fly   117 RVLFI-SRPQSDGQQQYILCNTK---------LDICPPLLDVLGQMAGNVERRLMNSVGDLKCNK 171
            |..|: |..::|   .:.|..|.         :|.|....|.|..:..| .|...||....:|:.
plant   513 REKFVESLLEAD---NFSLTTTSRGIHSALPMVDSCVKENDDLDVVKSN-HRARRNSSMAAECSS 573

  Fly   172 QQYKDIRLPSNFGLVGQRLIPPPQSNRNRNIQHE-----RRSLPIYKQRESILNVLQRDQVLIIK 231
            .:.|                   |.|:.:..:::     |.:|||.:.::.||..|:...||::.
plant   574 LKQK-------------------QENKKKMQKYKDMLKTRAALPISEVKKDILQKLKEKDVLVVC 619

  Fly   232 GATGSGKSTQLPQYILEWAAE--HRAPVRIVVSQPRRIAAISVSERISKERGEAP----GTTVGY 290
            |.|||||:||:||:||:...:  |.....|:.:|||   ||:|::|::.||.|.|    .:.|.|
plant   620 GETGSGKTTQVPQFILDDMIDSGHGGYCNIICTQPR---AITVAQRVADERCEPPPGFDNSVVAY 681

  Fly   291 NIRMNRQCSSNTVLMLTTSGCLLRALAMDKKSFFKNTTHLIIDEAHERDLDTDFLLLATKLELQK 355
            .:|.....|..|.|:..|:|.|||.|..|  :..|:.||:|:||.|||.|..||||:..|..::|
plant   682 QVRHQNARSDKTRLLFCTTGILLRKLVGD--TTLKDVTHIIVDEVHERSLMGDFLLIILKSLIEK 744

  Fly   356 N------PHLRLVLMSATMDLEALSNYFGGGTVMDVEGRSFEVSIYHLEDILSKTGYM------- 407
            .      |.|:::|||||:|....|.|||...::..:||:..|:.|.||||..:|.|:
plant   745 QSWDNALPKLKVILMSATVDAHQFSRYFGQCPIITAQGRTHPVTTYFLEDIYERTKYLLASDSPA 809

  Fly   408 ----HPRMEKFLGK---PTGKETPSELLAAYYGGNTIVHPD----------------IDNDLIVS 449
                ...:...||.   |.||:   .|:.|.:|.:.:|..|                :|.||:..
plant   810 ALSSDTSITDKLGSVNVPRGKK---NLMLAGWGDSYLVSEDSLNTSYDSIKYIASAVVDYDLLEE 871

  Fly   450 LLELLLRQGDAGAVIVYLPGYSDMTSLLARLESS-----------LPREQITIILLHSQVDNSEQ 503
            |:..:....:.||::|:|||.|::..||.||.:|           ||        |||.:.::||
plant   872 LICHIDDTCEEGAILVFLPGMSEINMLLNRLAASYRFRGASGDWLLP--------LHSSIASTEQ 928

  Fly   504 RKVFRTYP-GVRLKIILSTNIGQTSITIPDLLYVIDTGLAKMKTYDSTIDASQLTLTWISQADAK 567
            :|||...| |:| |:|::|||.:|||||.|::||||:|..|...|:.....|.:...|:|:|:|:
plant   929 KKVFLRPPKGIR-KVIIATNIAETSITIEDVVYVIDSGKHKENRYNPHKKLSSMVEDWVSKANAR 992

  Fly   568 QRAGRAGRVCHGNCYRLYDNDRMAR-MNLYTIPEIMRRTLDEICLLTKLAAPDKKIENFLALALD 631
            ||.||||||..|:|:.||...|..: |..|.:||::|..|.|:||..||.... :|:.||:.||:
plant   993 QRMGRAGRVKPGHCFSLYTRHRFEKLMRPYQVPEMLRVPLVELCLHIKLLGLG-QIKPFLSKALE 1056

  Fly   632 TPPKDAVMQSCSRLKLLGVLDERDEVTPLGHIVAELPLGVQIGKCLVYSIYLRCLDSMIIIAAYH 696
            .|.:.|:..:...|..:|.|:..:|:|||||.:|:||:.:.|||.|:|.....||..::.|||:.
plant  1057 PPSESAINSAILLLHKVGALEGDEELTPLGHHLAKLPVDLLIGKMLLYGGIFGCLSPILSIAAFL 1121

  Fly   697 S-VRDPFVLNIERGKKSGQQISRVLFA--------------GDGMSDSLAVIKLYEEFTNLKR-- 744
            | .:.|||.     .|..|.:.||..|              .|..||.|.::..||::..:..
plant  1122 SCCKSPFVY-----AKDEQNVDRVKLALLSDKLESSSNLNNNDRQSDHLLMVVAYEKWVRILHEQ 1181

  Fly   745 --KDIGDFCERNFICRNAMEMF----VSAASTLRDTVYRIFRFSEASARLASSF----------- 792
              |....|||..|:..:.|.|.    |.....|.|  ..:....:...|...:|
plant  1182 GFKAAESFCESKFLNSSVMRMMRERRVEFGMLLAD--IGLINLPKGKGRRKENFDVWFSDKTQPF 1244

  Fly   793 ---NNDTNMIRLALTAGLYPKLA--YMDRENK----NQLVA---EGDPLVQVSRSSCLRGKKKQK 845
               :.:..:::..|.|||.|.:|  .::|..|    .|..|   :|...|.:.|:|.   .|..|
plant  1245 NMYSQEPEVVKAILCAGLCPNIAEGLVNRLTKPAEETQRYAVWHDGKREVHIHRNSI---NKNCK 1306

  Fly   846 DLASEWILFVEKTRTADQISSLEHTTLVSGLMVALAGGKRFITEAHGSEMLLCLDSWIRLKCPAE 910
            .....:|:|:||..| .::..|:.||:||...:.|.||...:....||   :.:|.|::|..||:
plant  1307 AFQYPFIVFLEKLET-KKVVYLQDTTVVSPFSILLFGGSINVHHQSGS---VTIDGWLKLTAPAQ 1367

  Fly   911 FGLQLHKVRMLTDREFAKLV-ATRKLSLMSDFIGPETVRRLLEADVP 956
            ..:...::|:........|: ...|..::.:.:....|..|:|...|
plant  1368 TAVLFKELRLTLHSILKDLIRKPEKSGIVHNEVVKSMVHLLIEEGKP 1414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8915	NP_001285369.1	R3H	64..123	CDD:100064	16/74 (22%)
		DEXDc	214..395	CDD:214692	74/192 (39%)
		DEXDc	226..368	CDD:238005	62/153 (41%)
		HELICc	479..575	CDD:197757	44/107 (41%)
		HA2	648..733	CDD:214852	34/99 (34%)
		OB_NTP_bind	783..884	CDD:285018	30/123 (24%)
AT1G58050	NP_176102.1	DSRM	396..476	CDD:294045	15/83 (18%)
		HrpA	558..1323	CDD:224557	256/813 (31%)
		DEXDc	615..762	CDD:238005	61/151 (40%)
		Helicase_C	871..1002	CDD:278689	56/139 (40%)
		HA2	1074..1168	CDD:214852	34/98 (35%)
		OB_NTP_bind	1209..1345	CDD:285018	33/141 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278674at2759
OrthoFinder	1	1.000	-	-		FOG0000258
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18934
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920