DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8915 and AT1G48650

DIOPT Version :9

Sequence 1:	NP_001285369.1	Gene:	CG8915 / 32715	FlyBaseID:	FBgn0030833	Length:	976	Species:	Drosophila melanogaster
Sequence 2:	NP_001154411.1	Gene:	AT1G48650 / 841287	AraportID:	AT1G48650	Length:	1206	Species:	Arabidopsis thaliana

Alignment Length:	1023	Identity:	302/1023 - (29%)
Similarity:	497/1023 - (48%)	Gaps:	170/1023 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 DAGDKLKSEDEKMLRQLVDD----------FLQSCEPEKQLPGLTKAQR--SHVHRLAQHRGLKT 108
            |.|   .|:.::|....:|:          .|::.|.::.:....|.:|  .|:..||...||.:
plant   117 DVG---SSQSQQMAGSTLDNIDQWRFKLTMLLRNKEDQEVVSRERKDRRDFDHISALATRMGLHS 178

  Fly   109 --------VSKGPEENRVLFISRPQSDG---QQQYIL---------------CNTKLDICPPL-- 145
                    :||.|..|     .||..|.   |::.:|               .:.|..:.|.:
plant   179 RQYSKIVVISKAPLPN-----YRPDLDDKRPQREVVLPFGLQSEVDAHLHSFLDQKKTLIPEMPR 238

  Fly   146 ---LDVLGQMAGNVERR---LMNSVG----------DLKCNKQQYKDIRLPSNFGLVGQRLIPPP 194
               .:.|....||.|..   :.||:.          .||..:||:.|  .|....:||
plant   239 QNSSESLANGYGNYETPETVMQNSLARERILRPRSLQLKSKQQQWVD--SPEGQKMVG------- 294

  Fly   195 QSNRNRNIQHERRSLPIYKQRESILNVLQRDQVLIIKGATGSGKSTQLPQYILEWAAE--HRAPV 257
                      .|::||.||:::::|..:..:||:::.|.||.||:|||||||||...|  ..|..
plant   295 ----------FRKTLPAYKEKDALLKAIAANQVVVVSGETGCGKTTQLPQYILESEIEAARGATC 349

  Fly   258 RIVVSQPRRIAAISVSERISKERGEAPGTTVGYNIRMNRQCSSNTVLMLTTSGCLLRALAMDKKS 322
            .|:.:|||||:|||||||::.||||..|.:|||.:|:......:|.|:..|:|.|||.|.:|:.
plant   350 SIICTQPRRISAISVSERVAAERGEQIGESVGYKVRLEGMRGRDTRLLFCTTGVLLRRLLVDRS- 413

  Fly   323 FFKNTTHLIIDEAHERDLDTDFLLLATKLELQKNPHLRLVLMSATMDLEALSNYFGGGTVMDVEG 387
             .|..||:::||.|||.::.||||:..|..|.:.|.|:|:|||||::.|..|:||||...|.:.|
plant   414 -LKGVTHVVVDEIHERGMNEDFLLIVLKDLLPRRPDLKLILMSATLNAELFSSYFGGAPAMHIPG 477

  Fly   388 RSFEVSIYHLEDILSKTGY---MHPRMEKFLGKPTGK----------------ETPSELLAAYYG 433
            .::.|..:.|||.|..:||   .:.:::.:..:.|.|                .....|.||.:.
plant   478 FTYPVRAHFLEDYLETSGYRLTTYNQIDDYGEEKTWKMQKQAQFKKRKSLISSAVEDALEAADFK 542

  Fly   434 GN--------TIVHPD-IDNDLIVSLLELLLRQGDAGAVIVYLPGYSDMTSLLARLES-SLPREQ 488
            |.        :...|| |..:||.::|..:::....|||:|::.|:.|:.||..:||: ||..:.
plant   543 GYNFRTRDSLSCWSPDSIGFNLIENVLCHIVKGERPGAVLVFMTGWDDINSLKNQLEAHSLLGDP 607

  Fly   489 ITIILL--HSQVDNSEQRKVFRTYP-GVRLKIILSTNIGQTSITIPDLLYVIDTGLAKMKTYDST 550
            ..::||  |..:.:||||.:|...| |:| ||:|:||:.:|||||.|::||||.|.||..:||:.
plant   608 NKVLLLACHGSMASSEQRLIFDRPPEGIR-KIVLATNMAETSITINDVVYVIDCGKAKETSYDAL 671

  Fly   551 IDASQLTLTWISQADAKQRAGRAGRVCHGNCYRLYDNDRMARMNLYTIPEIMRRTLDEICLLTKL 615
            .:...|..:|||:|.|:||.||||||..|.||.||..........|..||::|..|..:||..|.
plant   672 NNTPCLLPSWISKAAARQRRGRAGRVMPGECYHLYPRCVYEAFADYQQPELLRTPLQSLCLQIKS 736

  Fly   616 AAPDKKIENFLALALDTPPKDAVMQSCSRLKLLGVLDERDEVTPLGHIVAELPLGVQIGKCLVYS 680
            .... .|..||:.||..|...:|..:...||::|.||:.:.:||||..::.||:..::||.|:..
plant   737 LGLG-SISEFLSRALQPPEALSVQNAVEYLKIIGALDDDENLTPLGKNLSMLPVEPKLGKMLILG 800

  Fly   681 IYLRCLDSMIIIAAYHSVRDPFVLNIERGKKSGQQISRVLFAGDGMSDSLAVIKLYEEFTNLKRK 745
            ....|||.::.:.|..||||||::..:  ||...:.:|..|:|...||.|.:::.|..:.:.:|.
plant   801 AIFNCLDPVMTVVAGLSVRDPFLMPFD--KKDLAETARSKFSGRDYSDHLTLVRAYNGWKDAERT 863

  Fly   746 DIG-DFCERNFICRNAMEMFVSAASTLRDTVYRIFRFSEAS----ARLASSFNNDTNMIRLALTA 805
            ..| |:|.:||:....::    |..::|...:.:.:  |||    ....|..::|.:::|..:.|
plant   864 HSGYDYCWKNFLSSQTLK----AMDSMRKQFFNLLK--EASLIDNIEGCSKLSHDEHLVRAIICA 922

  Fly   806 GLYPKLAYMDRENKN---QLVAEGDPLVQVSRSSCLRGKKKQKDLASEWILFVEKTRTADQISS- 866
            |::|.:..:..:.|:   :.:.:|..|:.   ||.:.|....  :...|::|.:|.:    ::|
plant   923 GMFPGVCSVVNKEKSITLKTMEDGQVLLY---SSSVNGNVPM--IPFPWLVFNDKVK----VNSV 978

  Fly   867 -LEHTTLVSGLMVALAGGKRFITEAHGSEMLLCLDSWIRLKCPAEFGLQ--LHKVRMLTDREFAK 928
             |..:|.||..::.|.|.|  |:.......|..|..::      ||.::  |....:...||..:
plant   979 FLRDSTAVSDSVLLLFGDK--ISSGGFDGHLKMLGGYL------EFFMKPTLAYTYLSLKRELDE 1035

  Fly   929 LVATRKLSLMSDFIGPETVRRLLEADVPSTCLAEGKSLLDRDNCDNDF 976
            |:..:       .:.|:     |:..:....:...:.|:..|.|:..|
plant  1036 LIQNK-------LVNPK-----LDIQLYDKLMTAIRLLVSEDQCEGRF 1071

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8915	NP_001285369.1	R3H	64..123	CDD:100064	15/78 (19%)
		DEXDc	214..395	CDD:214692	81/182 (45%)
		DEXDc	226..368	CDD:238005	70/143 (49%)
		HELICc	479..575	CDD:197757	46/99 (46%)
		HA2	648..733	CDD:214852	30/84 (36%)
		OB_NTP_bind	783..884	CDD:285018	25/109 (23%)
AT1G48650	NP_001154411.1	HrpA	276..1127	CDD:224557	271/856 (32%)
		DEXDc	316..458	CDD:238005	70/143 (49%)
		Helicase_C	567..660	CDD:278689	38/93 (41%)
		HA2	768..851	CDD:214852	30/84 (36%)
		OB_NTP_bind	888..998	CDD:285018	26/122 (21%)
		dsrm	1102..1163	CDD:278464
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278674at2759
OrthoFinder	1	1.000	-	-		FOG0000258
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820