DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8915 and AT2G35920

DIOPT Version :9

Sequence 1:	NP_001285369.1	Gene:	CG8915 / 32715	FlyBaseID:	FBgn0030833	Length:	976	Species:	Drosophila melanogaster
Sequence 2:	NP_001323636.1	Gene:	AT2G35920 / 818165	AraportID:	AT2G35920	Length:	1027	Species:	Arabidopsis thaliana

Alignment Length:	742	Identity:	251/742 - (33%)
Similarity:	380/742 - (51%)	Gaps:	80/742 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 RRSLPIYKQRESILNVLQRDQVLIIKGATGSGKSTQLPQYIL--EWAAEHRAPVRIVVSQPRRIA 268
            |..||.:|.:|..||.:.::|||::.|.||.||:|||||:||  |.::...|...|:.:|||||:
plant   257 REKLPAFKMKEEFLNSVSQNQVLVVSGETGCGKTTQLPQFILEEEISSLRGADCNIICTQPRRIS 321

  Fly   269 AISVSERISKERGEAPGTTVGYNIRMNRQCSSNTVLMLTTSGCLLRALAMDKKSFFKNTTHLIID 333
            ||||:.|||.||||:.|.:|||.||:..:.|..|.|:..|:|.|||.|..|..  ..|.:||::|
plant   322 AISVASRISAERGESIGESVGYQIRLESKRSDQTRLLFCTTGVLLRRLIEDPN--LTNVSHLLVD 384

  Fly   334 EAHERDLDTDFLLLATKLELQKNPHLRLVLMSATMDLEALSNYFGGGTVMDVEGRSFEVSIYHLE 398
            |.|||.::.||||:..:..|.:.|.|||:|||||::.:..|.|||....|.:.|.:|.|:...||
plant   385 EIHERGMNEDFLLIILRDLLPRRPDLRLILMSATINADMFSTYFGNSPTMHIPGFTFPVAELFLE 449

  Fly   399 DILSKTGYMHPRME--KFLGKPTGKETPSE----------------------------LLAAYYG 433
            |:|.|:.|.....:  .:.|...|:...||                            .|.|:.|
plant   450 DVLEKSRYNIKSSDSGNYQGSSRGRRRESESKKDDLTTLFEDIDINSHYKSYSSATRNSLEAWSG 514

  Fly   434 GNTIVHPDIDNDLIVSLLELLLRQGDAGAVIVYLPGYSDMTSLLARL-------ESSLPREQITI 491
            .      .||.||:.:.:|.:.|....||::|:|.|:.:::.||.::       :||    :..:
plant   515 A------QIDVDLVEATIEHICRLEGGGAILVFLTGWDEISKLLEKINMNNFLGDSS----KFLV 569

  Fly   492 ILLHSQVDNSEQRKVFRTYPGVRLKIILSTNIGQTSITIPDLLYVIDTGLAKMKTYDSTIDASQL 556
            :.||..:....||::|...|..:.||:|:|||.::||||.|::||:|.|.||..:||:....:.|
plant   570 LPLHGSMPTVNQREIFDRPPPNKRKIVLATNIAESSITIDDVVYVVDCGKAKETSYDALNKVACL 634

  Fly   557 TLTWISQADAKQRAGRAGRVCHGNCYRLYDNDRMARMNLYTIPEIMRRTLDEICLLTKLAAPDKK 621
            ..:|||:|.|.||.||||||..|.|||||..........|.:|||:|..|.|:||..| :.....
plant   635 LPSWISKASAHQRRGRAGRVQAGVCYRLYPKVIYDAFPQYQLPEIIRTPLQELCLHIK-SLQVGS 698

  Fly   622 IENFLALALDTPPKDAVMQSCSRLKLLGVLDERDEVTPLGHIVAELPLGVQIGKCLVYSIYLRCL 686
            |.:|||.||..|...||..:...||.:|.|::.:|:||||..:..||:...|||.|:.....:|:
plant   699 IGSFLAKALQPPDALAVENAIELLKTIGALNDVEELTPLGRHLCTLPVDPNIGKMLLIGAIFQCV 763

  Fly   687 DSMIIIAAYHSVRDPFVLNIERGKKSGQQISRVLFAGDGMSDSLAVIKLYEEFTNLKR-KDIGDF 750
            :..:.|||..:.|.||||.:.| |:...:..| .||||..||.:|::|.||.:.:.|| .:..||
plant   764 NPALTIAAALAYRSPFVLPLNR-KEEADEAKR-YFAGDSCSDHIALLKAYEGYRDAKRGGNEKDF 826

  Fly   751 CERNFICRNAMEMFVSAASTLRDTVYRIFRFSEASARLASSFNNDTNMIRLALTAGLYPKLAYMD 815
            |.:||:....:.|.....:...|.:..|....::.....:.::.|..||...|.|||||.:....
plant   827 CWQNFLSPVTLRMMEDMRNQFLDLLSDIGFVDKSKPNAYNQYSYDMEMISAVLCAGLYPNVVQCK 891

  Fly   816 RENKNQL----------VAEGDPLVQVSRSSCLRGKKKQKDLASEWILFVEKTRTADQISSLEHT 870
            |..|...          :..|....:|:..|.            .::::.||.:|....  :..:
plant   892 RRGKRTAFYTKELGKVDIHPGSVNARVNLFSL------------PYLVYSEKVKTTSVY--IRDS 942

  Fly   871 TLVSGLMVALAGGKRFITE-AHGSEML 896
            |.:|...:.:.||....:: ..|.|||
plant   943 TNISDYALLMFGGNLIPSKTGEGIEML 969

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8915	NP_001285369.1	R3H	64..123	CDD:100064
		DEXDc	214..395	CDD:214692	83/182 (46%)
		DEXDc	226..368	CDD:238005	71/143 (50%)
		HELICc	479..575	CDD:197757	38/102 (37%)
		HA2	648..733	CDD:214852	32/84 (38%)
		OB_NTP_bind	783..884	CDD:285018	20/110 (18%)
AT2G35920	NP_001323636.1	HrpA	225..941	CDD:224557	243/712 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	51	1.000	Domainoid score	I4329
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278674at2759
OrthoFinder	1	1.000	-	-		FOG0000258
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820