DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8915 and AT2G01130

DIOPT Version :9

Sequence 1:	NP_001285369.1	Gene:	CG8915 / 32715	FlyBaseID:	FBgn0030833	Length:	976	Species:	Drosophila melanogaster
Sequence 2:	NP_178223.2	Gene:	AT2G01130 / 814642	AraportID:	AT2G01130	Length:	1113	Species:	Arabidopsis thaliana

Alignment Length:	903	Identity:	282/903 - (31%)
Similarity:	459/903 - (50%)	Gaps:	127/903 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 LLDVLGQMAGNVERRLMNSV---GDLKCNKQQYKDIRLP-SNFGLVGQRLIPP-------PQSNR 198
            |.:.|.:.:..::|...|||   ..:....:.:.:..|| |...::.||.:..       ..|..
plant   145 LTEYLSKSSNRIDRVPANSVSRTSSISSTDEWFSEQPLPISATKILWQRSLQLRDRQQYWQASVE 209

  Fly   199 NRNIQHERRSLPIYKQRESILNVLQRDQVLIIKGATGSGKSTQLPQYIL--EWAAEHRAPVRIVV 261
            .:.:...|.|||.:|||.|:|..:.::||::|.|.||.||:||:||:||  |..|...|...|:.
plant   210 GQRMLDSRTSLPAFKQRHSVLTAISQNQVIVISGETGCGKTTQIPQFILESEIEANRGAFSSIIC 274

  Fly   262 SQPRRIAAISVSERISKERGEAPGTTVGYNIRMNRQCSSNTVLMLTTSGCLLRALAMDKKSFFKN 326
            :|||||:|:|||||::.||||..|.:|||.:|:......:|.|:..|:|.|||.|.:|:.  .:.
plant   275 TQPRRISAMSVSERVAYERGEQLGESVGYKVRLEGVKGRDTRLLFCTTGILLRRLLVDRN--LRG 337

  Fly   327 TTHLIIDEAHERDLDTDFLLLATKLELQKNPHLRLVLMSATMDLEALSNYFGGGTVMDVEGRSFE 391
            .||:|:||.|||.::.||||:..|..|.:...|:|:|||||:|.|..|:||||..|:.:.|.::.
plant   338 VTHVIVDEIHERGMNEDFLLIILKDLLSRRSELKLILMSATLDAELFSSYFGGAGVIYIPGFTYP 402

  Fly   392 VSIYHLEDILSKTGY-MHP-------------RMEKFLGKPTGKE-----------------TPS 425
            |..:.|||||..|.| :.|             :|.|.:.|....:                 :|.
plant   403 VRSHFLEDILEMTRYRLTPYNQIDDYGQERTWKMNKQIPKKRKSQITFVVEDALRAADFKEFSPE 467

  Fly   426 --ELLAAYYGGNTIVHPD-IDNDLIVSLLELLLRQGDAGAVIVYLPGYSDMTSLLARLESSLP-- 485
              |.|:.:|       || |..:||..||..:......|.::::|.|:.|::||..:|:.. |
plant   468 TRESLSCWY-------PDCIGFNLIEFLLCNICENEGPGGILIFLTGWDDISSLKEKLQIH-PIF 524

  Fly   486 --REQITIILLHSQVDNSEQRKVF-RTYPGVRLKIILSTNIGQTSITIPDLLYVIDTGLAKMKTY 547
              .:.:.::..|..::..|||.:| ....||| ||:|:|||.:|||||.|:.:|||.|.||..:|
plant   525 GNPDLVMLLACHGSMETFEQRLIFEEPASGVR-KIVLATNIAETSITINDVAFVIDCGKAKETSY 588

  Fly   548 DSTIDASQLTLTWISQADAKQRAGRAGRVCHGNCYRLYDN---DRMARMNLYTIPEIMRRTLDEI 609
            |:..:...|..:|||:..|:||.||||||..|.||.||..   |..|.   |.:|||:|..|..:
plant   589 DALNNTPCLLPSWISKVSAQQRRGRAGRVRPGQCYHLYPKCVYDAFAE---YQLPEILRTPLHSL 650

  Fly   610 CLLTK---LAAPDKKIENFLALALDTPPKDAVMQSCSRLKLLGVLDERDEVTPLGHIVAELPLGV 671
            ||..|   |.:    |..||:.||.:|...||.::.:.||::|.|||.:::|.||..:::||:..
plant   651 CLQIKSLNLGS----ISEFLSRALQSPELLAVQKAIAFLKIIGALDENEDLTTLGRYLSKLPMEP 711

  Fly   672 QIGKCLVYSIYLRCLDSMIIIAAYHSVRDPFVLNIERGKKSGQQISRVLFAGDGMSDSLAVIKLY 736
            ::||.|:....|.|||.::.:||..||||||:  ..:.||...:.::..|:.| .||.||:::.|
plant   712 KLGKMLILGAILGCLDPILTVAAGLSVRDPFL--TPQDKKDLAEAAKSQFSRD-HSDHLALVRAY 773

  Fly   737 EEFTNLKRKD-IGDFCERNFICRNAMEMFVSAASTLRDTVYRIFR---FSEASARLASSFNNDTN 797
            |.:...:.:. :.|:|.:||:...::.    |..:||...:.:.:   ..:.:..:.:|..||.|
plant   774 EGWKKAEEESAVYDYCWKNFLSIQSLR----AIDSLRKEFFSLLKDTGLIDGNPSICNSEGNDAN 834

  Fly   798 MIRLALTAGLYP---KLAYMDRENKNQLVAEGDPLVQVSRSSCLRGKKKQKDLASEWILFVEKTR 859
            :.|..:..|:||   .:.:.:|....:.:.:|..|: .|.|...|..|    :...|::|.||.:
plant   835 LTRAVICYGMYPGICSVVHNERSFSLKTMEDGQVLL-YSNSENARETK----IPYPWLVFNEKIK 894

  Fly   860 TADQISS--LEHTTLVSGLMVALAGG--KRFITEAHGSEMLLCLDSWIRLKCPAEFGLQ--LHKV 918
                ::|  |..:|..|...:.|.||  .:..|:.|    |..|..::      ||.::  :.::
plant   895 ----VNSVFLRDSTACSDSTLILFGGSISKGDTDGH----LKMLGGYL------EFFMKPDVAEI 945

  Fly   919 RMLTDREFAKLVATRKLSLMSDFIGPETVRRLLEADVPSTCLAEGKSLLDRDNCDNDF 976
            .....:|..:|:..:   |::..:..:..|.||.|.         :.|:..|.||..|
plant   946 YQTLKKELDELIQNK---LLNPKVDMQAHRELLSAI---------RLLVSEDGCDGRF 991

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8915	NP_001285369.1	R3H	64..123	CDD:100064
		DEXDc	214..395	CDD:214692	82/182 (45%)
		DEXDc	226..368	CDD:238005	67/143 (47%)
		HELICc	479..575	CDD:197757	40/100 (40%)
		HA2	648..733	CDD:214852	32/84 (38%)
		OB_NTP_bind	783..884	CDD:285018	26/107 (24%)
AT2G01130	NP_178223.2	DEXDc	225..402	CDD:214692	81/178 (46%)
		DEXDc	237..379	CDD:238005	67/143 (47%)
		Helicase_C	488..617	CDD:278689	49/130 (38%)
		HA2	688..770	CDD:214852	32/84 (38%)
		OB_NTP_bind	807..918	CDD:285018	26/119 (22%)
		dsrm	1025..1087	CDD:278464
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278674at2759
OrthoFinder	1	1.000	-	-		FOG0000258
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820