DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8915 and tdrd9

DIOPT Version :9

Sequence 1:	NP_001285369.1	Gene:	CG8915 / 32715	FlyBaseID:	FBgn0030833	Length:	976	Species:	Drosophila melanogaster
Sequence 2:	XP_012824154.2	Gene:	tdrd9 / 780352	XenbaseID:	XB-GENE-5893104	Length:	1346	Species:	Xenopus tropicalis

Alignment Length:	824	Identity:	236/824 - (28%)
Similarity:	389/824 - (47%)	Gaps:	146/824 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 LPIYKQRESILNVLQRDQVLIIKGATGSGKSTQLPQYILEWAAEHRAPVRIVVSQPRRIAAISVS 273
            |||.|.||.::.:::.:.|::|.|||||||||||||:||::..:|.....|||:|||:|||.|::
Frog   104 LPILKSREELIALIENNSVVVIHGATGSGKSTQLPQFILDYLRQHGQYCNIVVTQPRKIAARSIA 168

  Fly   274 ERISKERGEAPGTTVGYNIRMNRQCSSNTVLMLTTSGCLLRALAMDKKSFFKNTTHLIIDEAHER 338
            ..||.:|....|..|||.:.:.:..|..|.|:..|:|.||:.: :..||..: .||:.|||.|||
Frog   169 TWISNQRCWTLGGRVGYQVGLEKVASEETQLIYMTTGVLLQKI-VSAKSLLE-FTHIFIDEVHER 231

  Fly   339 DLDTDFLLLAT-KLELQKNPHLRLVLMSATMDLEALSNYFG--------GGTVMDVEGRSFEVSI 394
            ..:.||||:.. ||....:..::::|||||::.:..::||.        ...:.:|||:..::.:
Frog   232 TEEMDFLLMVVRKLLCTNSRFVKVILMSATINCKEFADYFAVPVLNKMTPAYIFEVEGKPHDIEV 296

  Fly   395 YHLEDILSKTGYMHPRMEKFLGKPTGKETPSELLAAYYGGNTIVHPDIDNDLIVSLLELL----- 454
            ::|:|:                    |:.|...:||:|....::..:: .::..||:.|.
Frog   297 FYLDDL--------------------KDIPQAKIAAHYSDEPLISKEM-YEVATSLIHLFDEMEK 340

  Fly   455 --LRQG--------DAGAVIVYLPGYSDMTSLLARLESSLPREQITIILLHSQVDNSEQRKVFRT 509
              |::|        ::.:|:|:|||..:: :.:..|.:::.::::.:..|||.:...||..||..
Frog   341 EELKKGKMSHKAYIESNSVLVFLPGLMEI-NYMHELFTNMVQKRLHVYPLHSSITLDEQNLVFMP 404

  Fly   510 YP--GVRLKIILSTNIGQTSITIPDLLYVIDTGLAKMKTYDSTIDASQLTLTWISQADAKQRAGR 572
             |  |.| |:||||||.::|||:||:.||||..|.|....|...:...|.|:|.|:.:..||.||
Frog   405 -PVIGYR-KVILSTNIAESSITVPDVKYVIDFCLTKTLVCDEETNYQSLRLSWASKTNCDQRKGR 467

  Fly   573 AGRVCHGNCYRLYDND---RMARMNLYTIPEIMRRTLDEICLLTKLAAPDKKIENFLALALDTPP 634
            ||||..|.|||....|   .:...|:  |||::|..|....|..||....:. ...||.||..|.
Frog   468 AGRVSKGYCYRFVQKDFWKNIIPENV--IPEMLRSPLGSTILKVKLLDMGEP-RALLATALSPPN 529

  Fly   635 KDAVMQSCSRLKLLGVL---DERD-------EVTPLGHIVAELPLGVQIGKCLVYSIYLRCLDSM 689
            ...:.::...||.||.|   .:|:       |:|.||.::|:||:.:|:||.:|......||:..
Frog   530 ITDIERTILLLKELGALAVSGKRENENPYDGELTFLGKVLAQLPVDLQLGKLIVLGHVFGCLEEC 594

  Fly   690 IIIAAYHSVRDPFVLNIERGKKSGQQISRVLFAGDGMSDSLAVIKLYEEFTNLKR-------KDI 747
            |||||..|:::.|.:.. |....|.: |::.|:|...||.:|::..::.:.:.|.       ||.
Frog   595 IIIAAALSLKNFFAMPF-RHLLDGYR-SKLSFSGSSRSDCIALVDAFKSWQSCKERGELRLSKDE 657

  Fly   748 GDFCERNFICRNAMEMFVSAASTLRDTVYRIFRFSEASARLASSFNNDTN-----MIRLALTAGL 807
            .::.:||:.   .::.....|:...|...||..|:....:.|.  :.|.|     ::::.:....
Frog   658 LEWGKRNYF---QIKRIREVAALYDDLKKRISHFNMHVTQPAR--DPDYNFKQRFILQIVMAGAF 717

  Fly   808 YPKLAYMDRENKNQLVAE---GDP-----LVQVSRSSCLRGKKKQKDLASEWILFVEKTRTADQI 864
            ||......:.::...|.:   .||     |..|...|.|..|:.|.       ||    |...|:
Frog   718 YPNYFTFGQSDERSAVRDLSAKDPRTTVVLKNVPNYSFLYYKQIQS-------LF----RQCGQV 771

  Fly   865 SSLEHTTLVSGLMVALAGGKRFITEAHGSEMLLCLDSWIRLKCPAEFGLQLHKVRMLTDREFAKL 929
            .|:            |..|.|...|..              :.|.|      :.:.||....|..
Frog   772 KSI------------LFDGSRAFVEFS--------------RNPTE------RFKTLTAVYLALK 804

  Fly   930 VATRKLSLMSDFIGPETVRRLLEADVPSTCLAEGKSLLDRDNCD 973
            :|..|:.|:.:....|.:.:   ||...|.|.     |.|.|.|
Frog   805 MAQLKIPLILNVHPTEDIEK---ADDTITSLK-----LSRINVD 840

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8915	NP_001285369.1	R3H	64..123	CDD:100064
		DEXDc	214..395	CDD:214692	70/189 (37%)
		DEXDc	226..368	CDD:238005	62/142 (44%)
		HELICc	479..575	CDD:197757	39/97 (40%)
		HA2	648..733	CDD:214852	32/94 (34%)
		OB_NTP_bind	783..884	CDD:285018	20/113 (18%)
tdrd9	XP_012824154.2	HrpA	60..>677	CDD:224557	192/606 (32%)
tdrd9	XP_012824154.2	Tudor_TDRD9	872..972	CDD:410502
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278674at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920