Protein Alignment CG8915 and Dhx30

DIOPT Version :10

• Sequence 1: NP_573208.1
• Gene: CG8915 / 32715
• FlyBaseID: FBgn0030833
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_001239612.1
• Gene: Dhx30 / 72831
• MGIID: 1920081
• Length: 1223
• Species: Mus musculus
• Alignment Length: 963
• Identity: 268/963 - (27%)
• Similarity: 461/963 - (47%)
• Gaps: 141/963 - (14%)

  Fly    43 GKQKTRPGKNAKADAGDKLKS------EDEKM---------LRQLVDDFLQSCEPEKQLPGLTKA 92
            |::|......|.|.|..||||      .:|.:         ||:|.:...:.|..:...|.|.|
Mouse   323 GRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRK- 386

  Fly    93 QRSHVHRLAQHRGLKTVSKGPEENRVLFISRPQSDGQQQYILCNTKLDICPPLLDVLGQMAGNVE 157
                :.....|..:.:....||       .|.|||            ||.|     ||:.:|.:.
Mouse   387 ----IEAFLSHYPVDSSWISPE-------LRLQSD------------DILP-----LGKDSGPLS 423

  Fly   158 RRLMNSVGDLKCNKQQYKDIRLPSNFGLVGQRLIPPPQSNRNRNIQHERRSLPIYKQRESILNVL 222
            ..:   .|.......:.:::||..:...:.:|..|         |..|...||:...|::||:.:
Mouse   424 DPI---TGKPYMPLSEAEEVRLSQSLLELWRRRGP---------IWQEAPQLPVDPHRDTILSAI 476

  Fly   223 QRDQVLIIKGATGSGKSTQLPQYILE-WAAEHR-APVRIVVSQPRRIAAISVSERISKERGEAPG 285
            ::..|::|.|.||.||:|::||.:|| :..|.| |...::::|||||:|:||::|:|.|.|.:..
Mouse   477 EQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLR 541

  Fly   286 TTVGYNIRM-NRQCSSNTVLMLTTSGCLLRALAMDKKSFFKNTTHLIIDEAHERDLDTDFLLLAT 349
            ..||:.:|: ::..:....|:..|.|.|||.|..:..  .:..:|:|:||.||||::|||||:..
Mouse   542 RNVGFQVRLESKPPARGGALLFCTVGILLRKLQSNPS--LEGVSHVIVDEVHERDVNTDFLLILL 604

  Fly   350 KLELQKNPHLRLVLMSATMDLEALSNYFGGGTVMDVEGRSFEVSIYHLEDILSKTG-YMHPRMEK 413
            |...:.||.|||||||||.|.|..|.||||..|:.|.|..:.|..::|||||:|.| :.:|...:
Mouse   605 KGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYPHRHR 669

  Fly   414 FLGKPTGKETPSELLAAYYGGNTIVHPDIDNDLIVSLLELLLRQGDAGAVIVYLPGYSDMTSLLA 478
            .      .|:..|..             :|.||:..|:..:..:|:.|.::.:|||:.::..:..
Mouse   670 H------HESEDECA-------------LDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQ 715

  Fly   479 RLESSLPREQITIILL--HSQVDNSEQRKVFRTYP-GVRLKIILSTNIGQTSITIPDLLYVIDTG 540
            ||:.:|...:...::|  ||.:...:|:.:|:..| ||| ||:|:|||.:||||:.|:::|:|:|
Mouse   716 RLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPLGVR-KIVLATNIAETSITVNDIVHVVDSG 779

  Fly   541 LAKMKTYDSTIDASQLTLTWISQADAKQRAGRAGRVCHGNCYRLYDNDRMARMNLYTIPEIMRRT 605
            |.|.:.||.....|.|...|:|:|:..||.|||||...|..|.|:...|:.:|..:.:|||:|..
Mouse   780 LHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTP 844

  Fly   606 LDEICLLTKLAAPDKKIENFLALALDTPPKDAVMQSCSRLKLLGVLDERDEVTPLGHIVAELPLG 670
            |:.:.|..|:..|:|....||:.|:|:|...||.::...|:.:||||:|:.:|.||..:|.:...
Mouse   845 LENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTD 909

  Fly   671 VQIGKCLVYSIYLRCLDSMIIIAAYHSVRDPFVLNIERGKKSGQQISRV--LFAGDGMSDSLAVI 733
            .::.|.:|.:...|||..::::.:. ..||||..:::    :..::.:|  |.:.|..||.||.:
Mouse   910 PRLAKAIVLAAIFRCLHPLLVVVSC-LTRDPFSSSLQ----NRAEVDKVKALLSHDSGSDHLAFV 969

  Fly   734 KL---YEEFTNLK-RKDIGDFCERNFICRNAMEMFVSAASTLRDTVYRIFRFSEAS-----ARLA 789
            :.   :||....: |....::.|.|.:...::...........:.:|..|...:.|     :...
Mouse   970 RAVAGWEEVLRWQDRTSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLPSAQC 1034

  Fly   790 SSFNNDTNMIRLALTAGLYPKLAYMDRENKNQLVAEGDPLVQVSRSSCLR-GKKKQKDLA----S 849
            :.::.:..:::..|.|||||.                  |:||.:....| ||.|...:.    |
Mouse  1035 NEYSEEEELVKGVLMAGLYPN------------------LIQVRQGKVTRQGKFKPNSVTYRTKS 1081

  Fly   850 EWILFVEKT--RTADQISSLEHTTLVSGLMVALAGGKRFI---TEAHGSEMLLCLDSWIRLKCPA 909
            ..||..:.|  |.|.::.|    ..::..|...:.|..|:   ::.|...:||..|..:.::...
Mouse  1082 GNILLHKSTINREATRLRS----RWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDG 1142

  Fly   910 EFGLQLHKVRMLTDREFAKLVA-TRKLSLMSDFIGPETVRRLLEADVPSTCLA 961
            .     .....|:|.:..:|.. :|.:.|:.:|  ...:.|::|..:.|...|
Mouse  1143 R-----RATISLSDSDLLRLEGDSRTVRLLREF--RRALGRMVERSLRSELAA 1188

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8915	NP_573208.1	R3H	67..123	CDD:460206	10/64 (16%)
		HrpA	208..>702	CDD:441249	177/500 (35%)
		OB_NTP_bind	799..884	CDD:400182	21/91 (23%)
Dhx30	NP_001239612.1	HrpA	455..>987	CDD:441249	192/567 (34%)
		OB_NTP_bind	1044..1131	CDD:400182	25/108 (23%)