Protein Alignment CG8915 and Dhx34

DIOPT Version :10

• Sequence 1: NP_573208.1
• Gene: CG8915 / 32715
• FlyBaseID: FBgn0030833
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_001258381.1
• Gene: Dhx34 / 684903
• RGDID: 1584452
• Length: 1143
• Species: Rattus norvegicus
• Alignment Length: 1088
• Identity: 281/1088 - (25%)
• Similarity: 429/1088 - (39%)
• Gaps: 311/1088 - (28%)

  Fly    87 PGLTKAQRSHVHRLAQHRGLKTVSKGPE-------ENRVL----------FISRPQSDGQ----- 129
            |..|:..|.|..|  .|.......:.||       |.|.|          :|.|...:.|
  Rat     3 PPRTREGRDHRDR--DHHRAPRKEEAPEKWDWNCPETRCLLEDVFFRDEDYIRRGSEECQKFWAF 65

  Fly   130 ----QQYILCNTKLDICPPLLDVLGQMAGNVERRLMNSVGDLKCNKQQYKDIRLPSNFGLVGQ-- 188
                |:|....|......|     ||....:.     ::.||.|.    .|.|...|..::|.
  Rat    66 FERLQKYQHLKTSQKEKDP-----GQPKHGIA-----ALADLPCT----YDPRYRINLSILGPDT 116

  Fly   189 -------RLIPPPQSNRNR-------------------NIQHERRSLPIYKQRESILNVLQRDQV 227
                   :.:||.:.:..|                   .:|.||.:|||.:....||..|:..||
  Rat   117 RGRHGPGKGLPPERVSEFRRALLHYLDFQQKQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQV 181

  Fly   228 LIIKGATGSGKSTQLPQYILEWAAEHRAPVRIVVSQPRRIAAISVSERISKERGEAPGTTVGYNI 292
            :::.|.||.|||||:|||:|.....|     :..:||||||.||:::|:..|.....|:.|||.|
  Rat   182 VVVAGDTGCGKSTQVPQYLLAAGFSH-----VACTQPRRIACISLAKRVGFESLSQYGSQVGYQI 241

  Fly   293 RMNRQCSSNTVLMLTTSGCLLRALAMDKKSFFKNTTHLIIDEAHERDLDTDFLLLATKLELQKNP 357
            |.....|:.|.::..|.|.|||.:..:.:  ......||:||.|||.|..||||...:..|.:.|
  Rat   242 RFESTRSAATKIVFLTVGLLLRQIQCEPR--LPQYQVLIVDEVHERHLHNDFLLGVLQRLLPQRP 304

  Fly   358 HLRLVLMSATMDLEALSNYFGGGTVMDVEGRSFEVSIYH----LEDILSKTGYMHPRMEKFLGKP 418
            .|:::|||||:::...|:||....|:.|.||.|.:::.:    .|...||:..:.||  .||
  Rat   305 DLKVILMSATINISLFSSYFSHAPVVQVPGRLFPITVVYQPQEAEQSASKSEKLDPR--PFL--- 364

  Fly   419 TGKETPSELLAAYYGGNTIVHPDIDNDLIVSLLELLLRQGDAGAVIVYLPGYSDMTSLLARLESS 483
                   .:|.|           |||.         ....:.|.::|:|.|.::::::|...::.
  Rat   365 -------RVLEA-----------IDNK---------YPPEERGDLLVFLSGMAEISTVLDAAQAY 402

  Fly   484 LPREQITIIL-LHSQVDNSEQRKVFRTYP-GVRLKIILSTNIGQTSITIPDLLYVIDTGLAKMKT 546
            ....|..::| |||.:..::|.|||...| ||| |.||||||.:||:||..:.:|:|:|..|..:
  Rat   403 ATLTQRWVVLPLHSALSVADQDKVFDVAPAGVR-KCILSTNIAETSVTIDGIRFVVDSGKVKEMS 466

  Fly   547 YDSTIDASQLTLTWISQADAKQRAGRAGRVCHGNCYRLY---DNDRMARMNLYTIPEIMRRTLDE 608
            ||......:|...|||||.|:||.|||||...|.|||||   |.|..|.   |.:|||.|..||.
  Rat   467 YDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCYRLYAESDYDAFAP---YPVPEIRRVALDA 528

  Fly   609 ICLLTK-LAAPDKKIENFLALALDTPPKDAVMQSCSRLKLLGVLDERDEVTPLGHIVAELPLGVQ 672
            :.|..| ::..|.:...|    ::.||..:|..:...|:..|.||..:.:||:|.::|:||:.|.
  Rat   529 LVLQMKSMSVGDPRTFPF----IEPPPAASVETAILYLQDQGALDSSEALTPIGSLLAQLPVDVV 589

  Fly   673 IGKCLVYSIYLRCLDSMIIIAAYHSVRDPFVLNIE------------------------------ 707
            |||.::........:.::.|||..||:.||..:.:
  Rat   590 IGKMMILGSMFSLAEPVLTIAAALSVQSPFTRSAQSNLDCATARRPLESDQGDPFTLFNVFNAWV 654

  Fly   708 --RGKKSG--------------------------------------------------------- 713
              :.::||
  Rat   655 QVKSERSGNSRKWCRRRGVEEHRLYEMANLRRQFKELLEDHGLLRGAQVVAPRDSYSRLQQRRER 719

  Fly   714 ---QQISRVLFAGDGMSDSLAVIKLYE---------EFTNLKRKDIGDFCERNFICRNAMEMFVS 766
               .|:.|....|.|....  |::|.|         |.:..:|.|..|..:..|..|:.:|...:
  Rat   720 QTLHQLKRQHEEGGGRRRK--VLRLQEDGCSSDEDHEGSASQRADSVDIQDVKFKLRHNLEQLQA 782

  Fly   767 AASTLRDTVYRIFRFSEASARLASSFNNDTNMIRLALTAGLYPKLAYMD-----RENKNQL---- 822
            |||:.:|..                 .:...:::|.|..||||:||..|     |::.:|:
  Rat   783 AASSAQDLT-----------------RDQLALLKLVLGRGLYPQLAVPDAFNSGRKDSDQIFHTQ 830

  Fly   823 -----------VAEGDPLV---QVSRSSCLRGKKKQKDLAS---EWILFVEKTRT-------ADQ 863
                       |....|.|   |...:|...|.:..||..|   :.:.||....|       ..:
  Rat   831 AKQGTVLHPTCVFANSPEVLHTQGPEASGREGSQDGKDQMSCKHQLLAFVSLLETNKPYLVNCVR 895

  Fly   864 ISSLEHTTLVSGLMVALAGGKRFITEAHGSEMLLCLDSWIRLK-CPAEFGLQLHKVRM------- 920
            |.:|:...|.|          |.| :.:|....|..|.|:.|: ..:|..::|....:
  Rat   896 IPALQSLLLFS----------RSI-DTNGDCSRLVADGWLELQLADSESAVRLLATSLRLRAHWE 949

  Fly   921 -LTDREFAKLVATRKLSLMSD----FIGPETV----RRLLE---ADVP 956
             ..||:.|:....|||....|    .:.|:.|    |.||:   |.||
  Rat   950 SALDRQLAQQAQRRKLEQEEDPESPAVSPQEVAALSRELLQFMAAKVP 997

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8915	NP_573208.1	R3H	67..123	CDD:460206	12/52 (23%)
		HrpA	208..>702	CDD:441249	175/503 (35%)
		OB_NTP_bind	799..884	CDD:400182	27/117 (23%)
Dhx34	NP_001258381.1	HrpA	161..>627	CDD:441249	177/512 (35%)
		OB_NTP_bind	798..909	CDD:400182	28/120 (23%)